The sole human cathelicidin peptide, LL-37, has been demonstrated to protect animals
against endotoxemia/sepsis. Low, physiological concentrations of LL-37 (≤ 1 μg/ml) were …

We show that an innate defense–regulator peptide (IDR-1) was protective in mouse models
of infection with important Gram-positive and Gram-negative pathogens, including methicillin …

Streptococcus salivarius is an early colonizer of human oral and nasopharyngeal epithelia,
and strain K12 has reported probiotic effects. An emerging paradigm indicates that …

Although considerable progress has been made in dissecting the signaling pathways
involved in the innate immune response, it is now apparent that this response can no longer …

Background Gene expression microarrays are a prominent experimental tool in functional
genomics which has opened the opportunity for gaining global, systems-level understanding …

When grown in divalent cation-limited medium, Pseudomonas aeruginosa becomes
resistant to cationic antimicrobial peptides and polymyxin B. This resistance is regulated by …

Abstract CARMAweb (Comprehensive R-based Microarray Analysis web service) is a web
application designed for the analysis of microarray data. CARMAweb performs data …

Incorporation of H2A. Z into the chromatin of inactive promoters has been shown to poise
genes for their expression. Here we provide strong evidence that H2A. Z is incorporated into …

In Saccharomyces cerevisiae, zinc cluster protein Pdr1 can form homodimers as well as
heterodimers with Pdr3 and Stb5, suggesting that different combinations of these proteins …

TonB-dependent receptors (TBDRs) mediate substrate-specific transport across the outer
membrane, utilizing energy derived from the proton motive force transmitted from the TonB …