Autism spectrum disorder (ASD) is typically characterized by common deficits in social skills
and repetitive/stereotyped behaviors. It is widely accepted that genetic and environmental …

Fear refers to an adaptive response in the face of danger, and the formed fear memory acts
as a warning when the individual faces a dangerous situation again, which is of great …

Ketamine, a rapid-acting antidepressant drug, has been used to treat major depressive
disorder and bipolar disorder (BD). Recent studies have shown that ketamine may increase …

Stimulator of IFN genes (STING) is a key molecule that binds to cyclic dinucleotides
produced by the cyclic GMP-AMP synthase to activate IFN expression and autophagy in the …

Acute administration of MK-801 (dizocilpine), an N-methyl-D-aspartate receptor (NMDAR)
antagonist, can establish animal models of psychiatric disorders. However, the roles of …

Alzheimer's disease (AD) is the most common chronic progressive neurodegenerative
disease in the elderly. It has an increasing prevalence and a growing health burden. One of …

Doublecortin (DCX) is transiently expressed in new-born neurons in the subventricular zone
(SVZ) and subgranular zone (SGZ) related to adult neurogenesis in the olfactory bulb (OB) …

The tree shrew (Tupaia belangeri) has long been proposed as a suitable alternative to non-
human primates (NHPs) in biomedical and laboratory research due to its close evolutionary …

Ketamine, a dissociative anaesthetic, has been used in the treatment of major depressive
disorder (MDD) as a rapid acting antidepressant drug. Recent studies have shown that …

Chinese tree shrews (Tupaia belangeri chinensis) are increasingly used as an alternative
experimental animal to non-human primates in studying viral infections. Guanylate-binding …