[HTML][HTML] Integrated lncRNA function upon genomic and epigenomic regulation

AB Herman, D Tsitsipatis, M Gorospe - Molecular Cell, 2022 - cell.com
Although some long noncoding (lnc) RNAs are known since the 1950s, the past 25 years
have uncovered myriad lncRNAs with diverse sequences, structures, and functions. The …

The emerging roles of circRNAs in cancer and oncology

LS Kristensen, T Jakobsen, H Hager… - Nature reviews Clinical …, 2022 - nature.com
Over the past decade, circular RNAs (circRNAs) have emerged as a large class of primarily
non-coding RNA molecules, many of which have key roles in cancer development and …

[HTML][HTML] Circular RNA: metabolism, functions and interactions with proteins

WY Zhou, ZR Cai, J Liu, DS Wang, HQ Ju, RH Xu - Molecular cancer, 2020 - Springer
Abstract Circular RNAs (CircRNAs) are single-stranded, covalently closed RNA molecules
that are ubiquitous across species ranging from viruses to mammals. Important advances …

Best practice standards for circular RNA research

AF Nielsen, A Bindereif, I Bozzoni, M Hanan… - Nature …, 2022 - nature.com
Circular RNAs (circRNAs) are formed in all domains of life and via different mechanisms.
There has been an explosion in the number of circRNA papers in recent years; however, as …

CircOGDH is a penumbra biomarker and therapeutic target in acute ischemic stroke

Y Liu, Y Li, J Zang, T Zhang, Y Li, Z Tan, D Ma… - Circulation …, 2022 - Am Heart Assoc
Background: Acute ischemic stroke (AIS) is a leading cause of disability and mortality
worldwide. Prediction of penumbra existence after AIS is crucial for making decision on …

[HTML][HTML] Exosomal RNAs: novel potential biomarkers for diseases—a review

J Wang, BL Yue, YZ Huang, XY Lan, WJ Liu… - International Journal of …, 2022 - mdpi.com
Exosomes are a subset of nano-sized extracellular vesicles originating from endosomes.
Exosomes mediate cell-to-cell communication with their cargos, which includes mRNAs …

[HTML][HTML] Emerging role of circular RNA–protein interactions

A Das, T Sinha, S Shyamal, AC Panda - Non-coding RNA, 2021 - mdpi.com
Circular RNAs (circRNAs) are emerging as novel regulators of gene expression in various
biological processes. CircRNAs regulate gene expression by interacting with cellular …

[HTML][HTML] Non-coding RNAs and epithelial mesenchymal transition in cancer: molecular mechanisms and clinical implications

H Khanbabaei, S Ebrahimi… - Journal of Experimental …, 2022 - Springer
Epithelial-mesenchymal transition (EMT) is a fundamental process for embryonic
development during which epithelial cells acquire mesenchymal characteristics, and the …

AUF1 ligand circPCNX reduces cell proliferation by competing with p21 mRNA to increase p21 production

D Tsitsipatis, I Grammatikakis, RK Driscoll… - Nucleic acids …, 2021 - academic.oup.com
Mammalian circRNAs can influence different cellular processes by interacting with proteins
and other nucleic acids. Here, we used ribonucleoprotein immunoprecipitation (RIP) …

[HTML][HTML] CircRNA—Protein Interactions in Muscle Development and Diseases

S Zheng, X Zhang, E Odame, X Xu, Y Chen… - International journal of …, 2021 - mdpi.com
Circular RNA (circRNA) is a kind of novel endogenous noncoding RNA formed through back-
splicing of mRNA precursor. The biogenesis, degradation, nucleus–cytoplasm transport …