Metallothioneins (MTs) are a group of cysteine-rich, universal, low molecular weight proteins
distributed widely in almost all major taxonomic groups ranging from tiny microbes to highly …

Zinc-responsive transcription factors are found in all kingdoms of life and include the
transcriptional activators ZntR, SczA, Zap1, bZip19, bZip23, and MTF-1, and transcriptional …

Zinc is an essential cofactor for many proteins. A key mechanism of zinc homeostasis during
deficiency is “zinc sparing” in which specific zinc-binding proteins are repressed to reduce …

Simple Summary Building ribosomes for cellular protein translation is a massive, energy-
consuming undertaking. The process is executed by all cells to replenish the relevant pools …

We previously identified the ZTRE (z inc t ranscriptional r egulatory e lement) in genes
involved in zinc homeostasis and showed that it mediates transcriptional repression in …

RNA Polymerase I (Pol I) has recently been recognized as a cancer therapeutic target. The
activity of this enzyme is essential for ribosome biogenesis and is universally activated in …

Autophagy, in part, is controlled by the repression and activation of autophagy-related (ATG)
genes. Here, we describe a new selective autophagy pathway that targets functional …

Transcription/processing of the ribosomal RNA (rRNA) precursor, as part of ribosome
biosynthesis, is intensively studied and characterized in eukaryotic cells. Here, we …

Objective This study aims to determine the right dose of zinc in the administration of pumpkin
seed flour to increase zinc levels in malnutrition Wistar rats. Methods This study was a true …

Background Stunting is a nutritional problem in the form of linear growth disturbance caused
by low intake of macro-and micronutrients. The prevalence of stunting in children aged 2-5 …