Label-free live optical imaging of dynamic cellular and subcellular features has been made
possible in recent years thanks to the advances made in optical imaging techniques …

Significance: After three decades, more than 75,000 publications, tens of companies being
involved in its commercialization, and a global market perspective of about USD 1.5 billion …

We present a completely label-free three-dimensional (3D) optical coherence tomography
(OCT)-based tissue dynamics imaging method for visualization and quantification of the …

An organoid is a three-dimensional (3D) in vitro cell culture emulating human organs. We
applied 3D dynamic optical coherence tomography (DOCT) to visualize the intratissue and …

While optical coherence tomography (OCT) provides a resolution down to 1 µm, it has
difficulties in visualizing cellular structures due to a lack of scattering contrast. By evaluating …

Dynamic contrast optical coherence tomography (DyC-OCT), an emerging imaging method,
utilizes fluctuation patterns in OCT signals to enhance contrast, thereby enabling non …

This study aims at demonstrating label-free drug-response-patterns assessment of different
tumor spheroids and drug types by dynamic optical coherence tomography (D-OCT). The …

Volumetric imaging of dynamic processes with microscopic resolution holds a huge potential
in biomedical research and clinical diagnosis. Using supercontinuum light sources and high …

This review examines the biological physics of intracellular transport probed by the coherent
optics of dynamic light scattering from optically thick living tissues. Cells and their …

To reveal the three-dimensional microstructure and calcium dynamics of human heart
organoids (hHOs), we developed a dual-modality imaging system combining the …