Targeted therapies against cancer have improved both survival and quality of life of patients.
However, metabolic rewiring evokes cellular mechanisms that reduce therapeutic …

Background & Aims Nonalcoholic steatohepatitis (NASH) occurs in the context of aberrant
metabolism. Glutaminolysis is required for metabolic reprograming of hepatic stellate cells …

Regulated by the tumor microenvironment, the metabolic network of the tumor is
reprogrammed, driven by oncogenes and tumor suppressor genes. The metabolic …

Metabolic reprogramming is recognized as one of the hallmarks of cancer. Alterations in the
micro-environmental metabolic characteristics are recognized as important tools for cancer …

The high glycolytic activity of multiple myeloma (MM) cells is the rationale for use of Positron
Emission Tomography (PET) with 18F-fluorodeoxyglucose ([18F] FDG) to detect both bone …

Pancreatic ductal adenocarcinoma (PDAC), which has a poor prognosis and nonspecific
symptoms and progresses rapidly, is the most common pancreatic cancer type. Inhibitors …

Purpose The purpose of this study was to compare dynamic 18 F-FGln PET/CT images of
healthy subjects and cancer patients and explore the best imaging phase for different …

Glutamine is an important source of nutrients for tumor proliferation. Designing new
glutamine-metabolizing PET imaging agents is useful for tumor diagnosis and treatment …

Multiple myeloma (MM) is a hematological disease characterized by the accumulation of
malignant plasma cells (PC) into and, more rarely, outside the bone marrow (BM)(1). In the …

Molecular Imaging Platform and Radiopharmaceutical Translational Research on Peking
University Cancer Hospital Page 354 367© The Author (s) 2024 V. Prasad (ed.), Beyond …