Genetics of spontaneous intracerebral hemorrhage: risk and outcome

H Guo, M You, J Wu, A Chen, Y Wan, X Gu… - Frontiers in …, 2022 - frontiersin.org
Spontaneous intracerebral hemorrhage (ICH) is a common fatal event without an effective
therapy. Of note, some familial aggregation and inherited tendency is found in ICH and …

Genome-Wide Studies in Ischaemic Stroke: Are Genetics Only Useful for Finding Genes?

C Gallego-Fabrega, E Muiño… - International Journal of …, 2022 - mdpi.com
Ischaemic stroke is a complex disease with some degree of heritability. This means that
heritability factors, such as genetics, could be risk factors for ischaemic stroke. The era of …

Biological age acceleration is lower in women with ischemic stroke compared to men

C Gallego-Fabrega, E Muiño, N Cullell… - Stroke, 2022 - Am Heart Assoc
Background: Stroke onset in women occurs later in life compared with men. The underlying
mechanisms of these differences have not been established. Epigenetic clocks, based on …

[HTML][HTML] VKORC1 single nucleotide polymorphisms in rodents in Spain

A Bermejo-Nogales, JAR Martín, J Coll, JM Navas - Chemosphere, 2022 - Elsevier
Rodents are considered one of the animal pests with the greatest impact on agricultural
production and public health. Anticoagulant rodenticides (ARs), used as one of the most …

Sex-Stratified Genome-Wide Association Study in the Spanish Population Identifies a Novel Locus for Lacunar Stroke

J Cárcel-Márquez, E Muiño, C Gallego-Fabrega… - Stroke, 2024 - ahajournals.org
BACKGROUND: Ischemic stroke (IS) represents a significant health burden globally,
necessitating a better understanding of its genetic underpinnings to improve prevention and …

KAT8 beyond Acetylation: A Survey of Its Epigenetic Regulation, Genetic Variability, and Implications for Human Health

L Yoo, D Mendoza, AJ Richard, JM Stephens - Genes, 2024 - mdpi.com
Lysine acetyltransferase 8, also known as KAT8, is an enzyme involved in epigenetic
regulation, primarily recognized for its ability to modulate histone acetylation. This review …

Biomodification of acenocoumarol by bifidobacteria

M Fragomeno, S Assad, P Mobili… - FEMS Microbiology …, 2021 - academic.oup.com
The increased interest of consumers in probiotic foods requires a deeper knowledge on the
possible interactions with drugs, because their pharmacological properties could be …

Association among VKORC1 rs9923231, CYP4F2 rs2108622, GGCX rs11676382 polymorphisms and acute ischemic stroke

S Iluţ, ŞC Vesa, V Văcăraş, D Şipoş-Lascu, C Bârsan… - Medicine, 2023 - journals.lww.com
Acute ischemic stroke is a major cause of morbidity and mortality worldwide, and genetic
factors play a role in the risk of stroke. Single nucleotide polymorphisms (SNPs) in the …

Independent and interactive effects of sex and CYP2C9 variant rs4918758 on ischemic stroke risk in Taiwan Biobank

JW Peng, ON Nfor, CC Ho, SY Hsu… - … journal of general …, 2022 - Taylor & Francis
Purpose Stroke is a complex health condition caused by multiple risk factors. We
investigated whether the Cytochrome P450 2C9 (CYP2C9) rs4918758 polymorphism and …

[PDF][PDF] Nghiên cứu tính đa hình gen CYP2C9, VKORC1 và liều thuốc chống đông kháng vitamin K ở bệnh nhân thay van tim cơ học

PT Thùy - 2020 - lib.yhn.edu.vn
Để hoàn thành luận án này, trước hết, tôi xin bày tỏ lòng tri ân sâu sắc tới GS. TS. Tạ Thành
Văn, Chủ tịch Hội đồng Trường, Nguyên Hiệu trưởng, Trưởng Bộ môn Hóa sinh Trường Đại …