The effects of extrinsic and intrinsic factors on neurogenesis

M Jiang, SE Jang, L Zeng - Cells, 2023 - mdpi.com
In the mammalian brain, neurogenesis is maintained throughout adulthood primarily in two
typical niches, the subgranular zone (SGZ) of the dentate gyrus and the subventricular zone …

Fetal brain damage in human fetuses with congenital cytomegalovirus infection: histological features and viral tropism

G Piccirilli, L Gabrielli, MP Bonasoni… - Cellular and Molecular …, 2023 - Springer
Human cytomegalovirus (HCMV) causes congenital neurological lifelong disabilities. To
date, the neuropathogenesis of brain injury related to congenital HCMV (cCMV) infection is …

Parental Folate Deficiency Inhibits Proliferation and Increases Apoptosis of Neural Stem Cells in Rat Offspring: Aggravating Telomere Attrition as a Potential …

Q Ren, G Zhang, C Dong, Z Li, D Zhou, L Huang, W Li… - Nutrients, 2023 - mdpi.com
The effect of maternal folate status on the fetal central nervous system (CNS) is well
recognized, while evidence is emerging that such an association also exists between fathers …

Changes in ADAR RNA editing patterns in CMV and ZIKV congenital infections

B Wales-McGrath, H Mercer, H Piontkivska - BMC genomics, 2023 - Springer
Background RNA editing is a process that increases transcriptome diversity, often through
Adenosine Deaminases Acting on RNA (ADARs) that catalyze the deamination of …

Regulation of Onecut2 by miR-9-5p in Japanese encephalitis virus infected neural stem/progenitor cells

S Sharma, A Majumdar, A Basu - Microbiology Spectrum, 2024 - Am Soc Microbiol
Japanese encephalitis virus (JEV) is one of the major neurotropic viral infections that is
known to dysregulate the homeostasis of neural stem/progenitor cells (NSPCs) and depletes …

Vav proteins in development of the brain: a potential relationship to the pathogenesis of congenital Zika syndrome?

AJ Norbury, LA Jolly, LP Kris, JM Carr - Viruses, 2022 - mdpi.com
Zika virus (ZIKV) infection during pregnancy can result in a significant impact on the brain
and eye of the developing fetus, termed congenital zika syndrome (CZS). At a morphological …

The anti-viral immune response of the adult host robustly modulates neural stem cell activity in spatial, temporal, and sex-specific manners

MN Chandwani, YS Kamte, VR Singh… - Brain, Behavior, and …, 2023 - Elsevier
Viruses induce a wide range of neurological sequelae through the dysfunction and death of
infected cells and persistent inflammation in the brain. Neural stem cells (NSCs) are often …

Mendelian randomization analysis suggests no associations of human herpes viruses with amyotrophic lateral sclerosis

Q Zheng, D Wang, R Lin, Y Chen, H Huang… - Frontiers in …, 2023 - frontiersin.org
Background The causal associations between infections with human herpes viruses (HHVs)
and amyotrophic lateral sclerosis (ALS) has been disputed. This study investigated the …

[HTML][HTML] Human neural progenitor cell models to study the antiviral effects and neuroprotective potential of approved and investigational human cytomegalovirus …

M Trevisan, A Pianezzola, M Onorati, L Apolloni… - Antiviral Research, 2024 - Elsevier
Human cytomegalovirus (HCMV) is the viral leading cause of congenital defects in
newborns worldwide. Many aspects of congenital CMV (cCMV) infection, which currently …

Perturbations in neural stem cell function during a neurotropic viral infection in juvenile mice

YS Kamte, MN Chandwani, NM London… - Journal of …, 2023 - Wiley Online Library
Viral infections of the central nervous system (CNS) often cause worse neurological
outcomes in younger hosts. Throughout childhood, the brain undergoes extensive …