Immunologic effects of vitamin D on human health and disease

N Charoenngam, MF Holick - Nutrients, 2020 - mdpi.com
Vitamin D is responsible for regulation of calcium and phosphate metabolism and
maintaining a healthy mineralized skeleton. It is also known as an immunomodulatory …

An update on the effects of vitamin D on the immune system and autoimmune diseases

C Sîrbe, S Rednic, A Grama, TL Pop - International journal of molecular …, 2022 - mdpi.com
Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis.
Experimental studies have shown that 1, 25-dihydroxyvitamin D (calcitriol) generates …

How does the immune system enter the brain?

JA Mapunda, H Tibar, W Regragui… - Frontiers in …, 2022 - frontiersin.org
Multiple Sclerosis (MS) is considered the most frequent inflammatory demyelinating disease
of the central nervous system (CNS). It occurs with a variable prevalence across the world. A …

[HTML][HTML] Gender differences in autoimmune disease

ST Ngo, FJ Steyn, PA McCombe - Frontiers in neuroendocrinology, 2014 - Elsevier
Autoimmune diseases are a range of diseases in which the immune response to self-
antigens results in damage or dysfunction of tissues. Autoimmune diseases can be systemic …

Vitamin D and risk of multiple sclerosis: a Mendelian randomization study

LE Mokry, S Ross, OS Ahmad, V Forgetta… - PLoS …, 2015 - journals.plos.org
Background Observational studies have demonstrated an association between decreased
vitamin D level and risk of multiple sclerosis (MS); however, it remains unclear whether this …

Role of vitamin D beyond the skeletal function: a review of the molecular and clinical studies

M Umar, KS Sastry, AI Chouchane - International journal of molecular …, 2018 - mdpi.com
The classical function of Vitamin D, which involves mineral balance and skeletal
maintenance, has been known for many years. With the discovery of vitamin D receptors in …

Vitamin D and multiple sclerosis: An update

C Pierrot-Deseilligny, JC Souberbielle - Multiple sclerosis and related …, 2017 - Elsevier
The most recent findings linking exposure to sun and vitamin D insufficiency to multiple
sclerosis (MS) are reviewed. Due to insufficient sunshine and changing lifestyles …

Major histocompatibility complex genomics and human disease

J Trowsdale, JC Knight - Annual review of genomics and human …, 2013 - annualreviews.org
Over several decades, various forms of genomic analysis of the human major
histocompatibility complex (MHC) have been extremely successful in picking up many …

Role of the blood–brain barrier in multiple sclerosis

GG Ortiz, FP Pacheco-Moisés, MÁ Macías-Islas… - Archives of medical …, 2014 - Elsevier
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system associated
with demyelination and axonal loss eventually leading to neurodegeneration. MS exhibits …

Regulation of immune function by vitamin D and its use in diseases of immunity

AS Vanherwegen, C Gysemans… - … and Metabolism Clinics, 2017 - endo.theclinics.com
The immune system, innate and adaptive, is a highly evolved and complex network,
essential for promoting survival in an environment full of potential pathogens, while …