Amiodarone (AMD) is a widely used antiarrhythmic drug prescribed to treat cardiac
tachyarrhythmias; however, AMD has been reported to provoke pulmonary fibrosis (PF) and …

Amiodarone is the most potent antiarrhythmic drug available and is commonly prescribed to
treat and prevent not only life-threatening ventricular arrhythmias but also atrial fibrillation …

Background Amiodarone is a highly effective treatment for supraventricular and ventricular
tachyarrhythmia; however, it could be associated with several serious adverse effects …

In preclinical hepatotoxicity testing cell based assays are frequently employed. However,
prediction of clinical drug induced liver injury (DILI) remains a major challenge. Here we …

SARS-CoV-2 is a systemic disease that can also impair the electrical stability of the
ventricles. Although a direct cardiac infection by the virus is plausible, the host's systemic …

Aims: The purpose of this study was to investigate the hepatoprotective effect of aqueous
and ethanolic extract of Crocus sativus in amiodarone-induced hepatotoxicity in rabbits …

Background Patients with Fontan circulation are known to be at high risk for developing
atrial tachyarrhythmias (AAs). Our objective was to examine the efficacy and safety of …

Background Liver cirrhosis is an uncommon but not rare side effect of amiodarone-induced
hepatotoxicity. Patients with hepatitis B virus and hepatitis C virus infections are at a high …

Purpose: To evaluate the probable toxic effects of amiodarone on retina, using
electrooculography (EOG) and electroretinography (ERG) testing methods. Patients and …

Aims Amiodarone (AM) is a highly efficient drug for arrhythmias treatment, but its extra-
cardiac adverse effects offset its therapeutic efficacy. Nanoparticles (NPs)-based delivery …