Serum amyloid A in inflammatory rheumatic diseases: a compendious review of a renowned biomarker

I Sorić Hosman, I Kos, L Lamot - Frontiers in Immunology, 2021 - frontiersin.org
Serum amyloid A (SAA) is an acute phase protein with a significant importance for patients
with inflammatory rheumatic diseases (IRD). The central role of SAA in pathogenesis of IRD …

A systematic review and meta-analysis on multiple cytokine gene polymorphisms in the pathogenesis of periodontitis

X Liu, H Li - Frontiers in immunology, 2022 - frontiersin.org
Aim Periodontitis is an inflammatory disease that destroys both soft and hard periodontal
tissues. However, a complex periodontal cytokine network remains unclear. This systematic …

Modulation of pro-oxidant and pro-inflammatory activities of m1 macrophages by the natural dipeptide carnosine

CG Fresta, A Fidilio, G Lazzarino, N Musso… - International journal of …, 2020 - mdpi.com
Carnosine is a natural endogenous dipeptide widely distributed in mammalian tissues,
existing at particularly high concentrations in the muscles and brain and possesses well …

Carnosine prevents Aβ-induced oxidative stress and inflammation in microglial cells: a key role of TGF-β1

G Caruso, CG Fresta, N Musso, M Giambirtone… - Cells, 2019 - mdpi.com
Carnosine (β-alanyl-L-histidine), a dipeptide, is an endogenous antioxidant widely
distributed in excitable tissues like muscles and the brain. Carnosine is involved in cellular …

The Th17 pathway in vascular inflammation: culprit or consort?

M Robert, P Miossec, A Hot - Frontiers in Immunology, 2022 - frontiersin.org
The involvement of IL-17A in autoimmune and inflammatory diseases has prompted the
development of therapeutic strategies to block the Th17 pathway. Promising results came …

Inflammation as the common biological link between depression and cardiovascular diseases: can carnosine exert a protective role?

G Caruso, CG Fresta, M Grasso… - Current Medicinal …, 2020 - ingentaconnect.com
Several epidemiological studies have clearly shown the high co-morbidity between
depression and Cardiovascular Diseases (CVD). Different studies have been conducted to …

Carnosine decreases pma-induced oxidative stress and inflammation in murine macrophages

G Caruso, CG Fresta, A Fidilio, F O'Donnell, N Musso… - Antioxidants, 2019 - mdpi.com
Carnosine is an endogenous dipeptide composed of β-alanine and L-histidine. This
naturally occurring molecule is present at high concentrations in several mammalian …

Expression of SAA1, SAA2 and SAA4 genes in human primary monocytes and monocyte-derived macrophages

C Jumeau, F Awad, E Assrawi, L Cobret… - PLoS …, 2019 - journals.plos.org
Circulating serum amyloid A (SAA) is increased in various inflammatory conditions. The
human SAA protein family comprises the acute phase SAA1/SAA2, known to activate a large …

[PDF][PDF] One year in review 2019: Behçet's syndrome

G Hatemi, E Seyahi, I Fresko, R Talarico… - Clin Exp …, 2019 - clinexprheumatol.org
Several epidemiologic studies report on the prevalence of Behçet's syndrome (BS) and
demographic and clinical findings in patients from different countries and ethnicities …

The role of Th17 cells in the pathogenesis of Behcet's disease

Y Nanke, T Yago, S Kotake - Journal of clinical medicine, 2017 - mdpi.com
Behcet's disease (BD) is a polysymptomatic and recurrent systemic vasculitis with a chronic
course and unknown cause. The pathogenesis of BD has not been fully elucidated; …