Long noncoding RNA expression profiling in cancer: challenges and opportunities

L Lorenzi, F Avila Cobos, A Decock… - Genes …, 2019 - Wiley Online Library
In recent years, technological advances in transcriptome profiling revealed that the
repertoire of human RNA molecules is more diverse and extended than originally thought …

The RNA Atlas expands the catalog of human non-coding RNAs

L Lorenzi, HS Chiu, F Avila Cobos, S Gross… - Nature …, 2021 - nature.com
Existing compendia of non-coding RNA (ncRNA) are incomplete, in part because they are
derived almost exclusively from small and polyadenylated RNAs. Here we present a more …

Integrative analysis identifies lincRNAs up-and downstream of neuroblastoma driver genes

D Rombaut, HS Chiu, B Decaesteker, C Everaert… - Scientific reports, 2019 - nature.com
Long intergenic non-coding RNAs (lincRNAs) are emerging as integral components of
signaling pathways in various cancer types. In neuroblastoma, only a handful of lincRNAs …

A neuronal enhancer network upstream of MEF2C is compromised in patients with Rett-like characteristics

E D'haene, R Bar-Yaacov, I Bariah… - Human molecular …, 2019 - academic.oup.com
Mutations in myocyte enhancer factor 2C (MEF2C), an important transcription factor in
neurodevelopment, are associated with a Rett-like syndrome. Structural variants (SVs) …

[HTML][HTML] A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing

K Verboom, W Van Loocke, PJ Volders… - …, 2018 - ncbi.nlm.nih.gov
MSTRG. 37538 is a lncRNA marked with one of the strongest genome-wide super-enhancer
sites of all identified unannotated lncRNAs (Figure 2C, D). In a complementary approach …

[PDF][PDF] Charting regulatory RNAs in the human transcriptome using RNA-sequencing

L Lorenzi - 2021 - biblio.ugent.be
Technological advances in RNA-sequencing technologies enabled the profiling of the
transcriptome to an unprecedented depth, revealing a variety of regulatory non-coding …

[PDF][PDF] A new computational framework for the classification and function prediction of long non-coding RNAs

S Deshpande - 2018 - pureportal.coventry.ac.uk
Long non-coding RNAs (lncRNAs) are known to play a significant role in several biological
processes. These RNAs possess sequence length greater than 200 base pairs (bp), and so …

[引用][C] Characterizing the Regulatory Elements of MEF2C During Brain Development

R Alatawna - 2020 - Ben-Gurion University of the Negev