Several proteomics approaches are available that are defined by the level (protein or
peptide) at which analysis takes place. The most widely applied method still is bottom-up …

Background: the prevalence of sarcopenia varies widely between studies. The objective of
this study was to assess the prevalence of sarcopenia in a representative sample of persons …

It is commonly known that enzymatic transformations are considerably more specific than
classical chemical reactions which usually lead to formation of byproducts. That is why the …

Fast, efficient characterization of proteins is becoming one of the hottest topics in the
bioanalytical community, especially for large-scale proteomic studies. As an attractive …

Miniaturized separation techniques have emerged as environmentally friendly alternatives
to available separation methods. Nano-liquid chromatography (nano-LC), microchip devices …

With the acceleration of proteome research, increasing attention has been paid to
multidimensional liquid chromatography–mass spectrometry (MDLC–MS) due to its high …

Reducing experimental variability, limiting contamination and increasing automation are
essential goals in the development of reliable analytical platforms for mass spectrometry …

In recent years, quantitative proteomic research attracts great attention because of the
urgent needs in biological and clinical research, such as biomarker discovery and …

Pepsin was immobilized on ethyl-bridged hybrid (BEH) particles, and digestion performance
was evaluated in a completely online format, with the specific intent of using the particles for …

Microfluidic system with multi-functional integration of high-throughput protein/peptide
separation ability has great potential for improving the identification capacity of biological …