Roles of miRNAs in regulating ovarian cancer stemness

C Zhi-Xiong - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
Ovarian cancer is one of the gynaecology malignancies with the highest mortality rate.
Ovarian cancer stem cell (CSC) is a subpopulation of ovarian cancer cells with increased …

One Host-Multiple Applications: Zebrafish (Danio rerio) as Promising Model for Studying Human Cancers and Pathogenic Diseases

K Dudziak, M Nowak, M Sozoniuk - International Journal of Molecular …, 2022 - mdpi.com
In recent years, zebrafish (ZF) has been increasingly applied as a model in human disease
studies, with a particular focus on cancer. A number of advantages make it an attractive …

Exosomal miR-4516 derived from ovarian cancer stem cells enhanced cisplatin tolerance in ovarian cancer by inhibiting GAS7

X Pan, X Shi, H Zhang, YG Chen, JH Zhou, FR Shen… - Gene, 2024 - Elsevier
Ovarian cancer (OC) is a devastating disease for women, with chemotherapy resistance
taking the lead. Cisplatin has been the first-line therapy for OC for a long time. However, the …

Identification of Tumor Suppressive Genes Regulated by miR-31-5p and miR-31-3p in Head and Neck Squamous Cell Carcinoma

S Oshima, S Asai, N Seki, C Minemura… - International journal of …, 2021 - mdpi.com
We identified the microRNA (miRNA) expression signature of head and neck squamous cell
carcinoma (HNSCC) tissues by RNA sequencing, in which 168 miRNAs were significantly …

Gas7 attenuates hepatocellular carcinoma progression and chemoresistance through the PI3K/Akt signaling pathway

WF Liu, QW Zhang, B Quan, F Zhang, M Li, SX Lu… - Cellular …, 2023 - Elsevier
Growth arrest-specific gene 7 (Gas7) was involved in various cellular functions, although its
specific roles and molecular mechanisms in hepatocellular carcinoma (HCC) remained …

SMAD9-MYCN positive feedback loop represents a unique dependency for MYCN-amplified neuroblastoma

K Tan, J Mo, M Li, Y Dong, Y Han, X Sun, Y Ma… - Journal of Experimental …, 2022 - Springer
Background Neuroblastoma (NB) is the most common extracranial solid tumor occurring
during childhood and high-risk NB patients have a poor prognosis. The amplified MYCN …

Circ_0078607 increases platinum drug sensitivity via miR-196b-5p/GAS7 axis in ovarian cancer

C Dai, SY Dai, Y Gao, T Yan, QY Zhou, S Liu, X Liu… - Epigenetics, 2023 - Taylor & Francis
Platinum-based chemotherapy is one of the predominant strategies for treating ovarian
cancer (OC), however, platinum resistance greatly influences the therapeutic effect. Circular …

Zebrafish as a neuroblastoma model: Progress made, promise for the future

S Li, KS Yeo, TM Levee, CJ Howe, ZP Her, S Zhu - Cells, 2021 - mdpi.com
For nearly a decade, researchers in the field of pediatric oncology have been using
zebrafish as a model for understanding the contributions of genetic alternations to the …

神经母细胞瘤动物模型研究进展与应用

谭志刚, 刘锦信, 郑楚雅, 廖文峰, 冯露平, 彭红丽… - 实验动物与比较 …, 2023 - slarc.org.cn
神经母细胞瘤(neuroblastoma, NB) 是儿童最常见的实体恶性肿瘤, 居我国儿童肿瘤发病率第四
位, 占儿童肿瘤死亡人数的15%, 高危患者存活率低. 目前对于NB 的发病及药物治疗机制知之甚 …

[HTML][HTML] The METTL3/miR-196a Axis Predicts Poor Prognosis in Non-small Cell Lung Cancer

Z Yang, J Hao, M Qiu, R Liu, H Mei, Q Zhang… - Journal of …, 2024 - ncbi.nlm.nih.gov
Background: METTL3 accelerates m6A modification to influence cancer progression
including non-small cell lung cancer (NSCLC). To illustrate the role and underlying …