Cryptococcosis

AC Gushiken, KK Saharia, JW Baddley - Infectious Disease Clinics, 2021 - id.theclinics.com
Cryptococcosis is an infection of global significance, affecting both immunocompromised
and immunocompetent hosts. Traditionally, 2 main species of yeasts caused cryptococcosis …

Antifungal drugs TDM: trends and update

B Kably, M Launay, A Derobertmasure… - Therapeutic Drug …, 2022 - journals.lww.com
Purpose: The increasing burden of invasive fungal infections results in growing challenges
to antifungal (AF) therapeutic drug monitoring (TDM). This review aims to provide an …

Adjunctive sertraline for HIV-associated cryptococcal meningitis: a randomised, placebo-controlled, double-blind phase 3 trial

J Rhein, KH Hullsiek, L Tugume… - The Lancet infectious …, 2019 - thelancet.com
Background Identifying new antifungals for cryptococcal meningitis is a priority given the
inadequacy of current therapy. Sertraline has previously shown in vitro and in vivo activity …

Mortality from HIV‐associated meningitis in sub‐Saharan Africa: a systematic review and meta‐analysis

MW Tenforde, AM Gertz, DS Lawrence… - African Journal of …, 2020 - journals.lww.com
Introduction: HIV-associated cryptococcal, TB and pneumococcal meningitis are the leading
causes of adult meningitis in sub-Saharan Africa (SSA). We performed a systematic review …

Treatment of invasive fungal diseases in cancer patients—Revised 2019 Recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society …

M Ruhnke, OA Cornely, M Schmidt‐Hieber, N Alakel… - Mycoses, 2020 - Wiley Online Library
Background Invasive fungal diseases remain a major cause of morbidity and mortality in
cancer patients undergoing intensive cytotoxic therapy. The choice of the most appropriate …

Consensus guidelines for the diagnosis and management of cryptococcosis and rare yeast infections in the haematology/oncology setting, 2021

CC Chang, V Hall, C Cooper… - Internal Medicine …, 2021 - Wiley Online Library
Cryptococcosis caused by the Cryptococcus neoformans–Cryptococcus gattii complex is an
important opportunistic infection in people with immunodeficiency, including in the …

Nano drug-delivery systems for management of AIDS: liposomes, dendrimers, gold and silver nanoparticles

FD Asl, M Mousazadeh, S Taji, A Bahmani… - …, 2023 - Taylor & Francis
AIDS causes increasing mortality every year. With advancements in nanomedicine, different
nanomaterials (NMs) have been applied to treat AIDS and overcome its limitations. Among …

[HTML][HTML] The Functional Implications of Broad Spectrum Bioactive Compounds Targeting RNA-Dependent RNA Polymerase (RdRp) in the Context of the COVID-19 …

BA Comunale, RJ Larson, E Jackson-Ward, A Singh… - Viruses, 2023 - mdpi.com
Background: As long as COVID-19 endures, viral surface proteins will keep changing and
new viral strains will emerge, rendering prior vaccines and treatments decreasingly effective …

New Insights Into Cryptococcus Spp. Biology and Cryptococcal Meningitis

E Temfack, T Boyer-Chammard, D Lawrence… - Current neurology and …, 2019 - Springer
Abstract Purpose of Review Defective cell–mediated immunity is a major risk factor for
cryptococcosis, a fatal disease if untreated. Cryptococcal meningitis (CM), the main …

Emerging concepts in HIV-associated cryptococcal meningitis

DS Lawrence, T Boyer-Chammard… - Current opinion in …, 2019 - journals.lww.com
Emerging concepts in HIV-associated cryptococcal meningitis : Current Opinion in Infectious
Diseases Emerging concepts in HIV-associated cryptococcal meningitis : Current Opinion in …