Implantable image sensors have the potential to revolutionize neuroscience. Due to their small form factor requirements; however, conventional filters and optics cannot be …
Emerging optical functional imaging and optogenetics are among the most promising approaches in neuroscience to study neuronal circuits. Combining both methods into a …
We present an implantable single-photon shank-based imager, monolithically integrated onto a single CMOS IC. The imager comprises of 512 single-photon avalanche diodes …
Neural interfaces bridge the nervous system and the outside world by recording and stimulating neurons. Combining electrical and optical modalities in a single, hybrid neural …
This paper presents a device for time-gated fluorescence imaging in the deep brain, consisting of two on-chip laser diodes and 512 single-photon avalanche diodes (SPADs) …
In neuroscience, optical techniques have become the leading method over electrophysiological techniques because of their ability to target defined populations upon …
This thesis describes the development of a minimally invasive integrated platform for all- optical neural stimulation and measurement (OptoSAM). The OptoSAM platform is a single …
ML Roukes - CLEO: Applications and Technology, 2022 - opg.optica.org
The Integrated Neurophotonics Paradigm Page 1 The Integrated Neurophotonics Paradigm Michael L. Roukes Departments of Physics, Applied Physics, and Bioengineering California …
The advent of genetically encoded voltage and calcium indicators and optogenetic probes has unlocked unprecedented capabilities, including near-single-action-potential recording …