Neuroepigenetics of ageing and neurodegeneration-associated dementia: an updated review

FA Mir, A Amanullah, BP Jain, Z Hyderi… - Ageing Research …, 2023 - Elsevier
Gene expression is tremendously altered in the brain during memory acquisition, recall, and
forgetfulness. However, non-genetic factors, including environmental elements, epigenetic …

Pathophysiological basis and promise of experimental therapies for Gulf War Illness, a chronic neuropsychiatric syndrome in veterans

M Kodali, T Jankay, AK Shetty, DS Reddy - Psychopharmacology, 2023 - Springer
This article describes the pathophysiology and potential treatments for Gulf War Illness
(GWI), which is a chronic neuropsychiatric illness linked to a combination of chemical …

[HTML][HTML] Oral nano-curcumin in a model of chronic Gulf War illness alleviates brain dysfunction with modulation of oxidative stress, mitochondrial function …

S Attaluri, M Arora, LN Madhu, M Kodali… - Aging and …, 2022 - ncbi.nlm.nih.gov
Unrelenting cognitive and mood impairments concomitant with incessant oxidative stress
and neuroinflammation are among the significant symptoms of chronic Gulf War Illness …

Ketamine Produces Antidepressant Effects by Inhibiting Histone Deacetylases and Upregulating Hippocampal Brain-Derived Neurotrophic Factor Levels in a …

A Ribeiro-Davis, DY Al Saeedy, FM Jahr… - … of Pharmacology and …, 2024 - ASPET
Approximately one-third of Gulf War veterans suffer from Gulf War Illness (GWI), which
encompasses mood disorders and depressive symptoms. Deployment-related exposure to …

[HTML][HTML] Brain-specific increase in leukotriene signaling accompanies chronic neuroinflammation and cognitive impairment in a model of Gulf war illness

S Attaluri, R Upadhya, M Kodali, LN Madhu… - Frontiers in …, 2022 - frontiersin.org
Persistent cognitive impairment is a primary central nervous system-related symptom in
veterans afflicted with chronic Gulf War Illness (GWI). Previous studies in a rat model have …

Mitigating neuroinflammation in Parkinson's disease: Exploring the role of proinflammatory cytokines and the potential of phytochemicals as natural therapeutics

P Sharma, A Kishore, I De, S Negi, G Kumar… - Neurochemistry …, 2023 - Elsevier
Parkinson's disease (PD) is one of the most prevalent neuroinflammatory illnesses,
characterized by the progressive loss of neurons in the brain. Proinflammatory cytokines …

Repeated exposure to chlorpyrifos is associated with a dose-dependent chronic neurobehavioral deficit in adult rats

ACR Ribeiro, E Hawkins, FM Jahr, JL McClay… - Neurotoxicology, 2022 - Elsevier
Organophosphate (OP) chemicals include commonly used pesticides and chemical warfare
agents, and mechanistically they are potent inhibitors of the cholinesterase (ChE) enzyme …

Hormonal changes in veterans with Gulf War Illness

G Bhatti, A Villalon, R Li, M Elammari, A Price, L Steele… - Life Sciences, 2023 - Elsevier
Abstract Aims Gulf War Illness (GWI) is a multi-system condition of complex etiology and
pathophysiology without specific treatment. There is an overlap between the symptoms of …

Epigenetic modification of histone acetylation in the sensorimotor cortex after intracerebral hemorrhage

T Nishio, T Inoue, Y Takamatsu, T Mishima… - Biomedical …, 2024 - jstage.jst.go.jp
Epigenetic regulation is involved in post-stroke neuroplasticity. We investigated the effects of
intracerebral hemorrhage (ICH) on histone acetylation and gene expression related to …

Organophospate-Induced Pathology: Mechanisms of Development, Principles of Therapy and Features of Experimental Studies

NV Goncharov, DA Belinskaia, PV Avdonin - Journal of Evolutionary …, 2023 - Springer
Organophosphates (OP) are one of the most common neurotoxic xenobiotics. In acute OP
poisoning, as a result of suppression of synaptic acetylcholinesterase (AChE) activity, a …