The locus coeruleus (LC), or 'blue spot', is a small nucleus located deep in the brainstem
that provides the far-reaching noradrenergic neurotransmitter system of the brain. This …

Over more than a century of research has established the fact that sleep benefits the
retention of memory. In this review we aim to comprehensively cover the field of “sleep and …

Sleep has been identified as a state that optimizes the consolidation of newly acquired
information in memory, depending on the specific conditions of learning and the timing of …

Despite the ubiquity of sleep across phylogeny, its function remains elusive. In this review,
we consider one compelling candidate: brain plasticity associated with memory processing …

A fundamental question in memory research is how our brains can form enduring memories.
In humans, memories of everyday life depend initially on the medial temporal lobe system …

The concept of 'sleeping on a problem'is familiar to most of us. But with myriad stages of
sleep, forms of memory and processes of memory encoding and consolidation, sorting out …

In many parts of the nervous system, experience-dependent refinement of neuronal circuits
predominantly involves synapse elimination. The role of sleep in this process remains …

Sleep has been implicated in the plastic cerebral changes that underlie learning and
memory. Indications that sleep participates in the consolidation of fresh memory traces come …

While the functions of sleep remain largely unknown, one of the most exciting and
contentious hypotheses is that sleep contributes importantly to memory. A large number of …

In this review, we present a new conceptual framework for the study of play behavior, a
hitherto puzzling array of seemingly purposeless and unrelated behavioral elements that are …