[HTML][HTML] The association between the neuroendocrine system and the tumor immune microenvironment: emerging directions for cancer immunotherapy

J Li, M Che, B Zhang, K Zhao, C Wan, K Yang - Biochimica et Biophysica …, 2023 - Elsevier
This review summarizes emerging evidence that the neuroendocrine system is involved in
the regulation of the tumor immune microenvironment (TIME) to influence cancer …

[HTML][HTML] Exploring Predictive and Prognostic Biomarkers in Colorectal Cancer: A Comprehensive Review

K Ashouri, A Wong, P Mittal, L Torres-Gonzalez, JH Lo… - Cancers, 2024 - mdpi.com
Simple Summary Colorectal cancer is a major health concern globally, and finding ways to
improve treatment outcomes is crucial. This review explores the role of biomarkers …

Acetylcholine, another factor in breast cancer

JP Muñoz, GM Calaf - Biology, 2023 - mdpi.com
Simple Summary Our previous work established that organophosphorus pesticides
increased acetylcholine (ACh) levels and promoted mammary gland tumor development in …

Vagus innervation in the gastrointestinal tumor: current understanding and challenges

YT Li, WZ Yuan, WL Jin - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
The vagus nerve (VN) is the main parasympathetic nerve of the autonomic nervous system.
It is widely distributed in the gastrointestinal tract and maintains gastrointestinal homeostasis …

Crosstalk between the nervous system and tumor microenvironment: Functional aspects and potential therapeutic strategies

L Wang, J Ge, H Han, Y Jia, Y Qin - Cancer Letters, 2024 - Elsevier
Recent advancements in understanding the tumor microenvironment (TME) have
highlighted the critical role of the nervous system in cancer progression. This review …

Nerve-tumor crosstalk in tumor microenvironment: From tumor initiation and progression to clinical implications

Z Zhang, ZG Lv, M Lu, H Li, J Zhou - … et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
The autonomic nerve system (ANS) innervates organs and tissues throughout the body and
maintains functional balance among various systems. Further investigations have shown …

Sexual dimorphism in colorectal cancer: molecular mechanisms and treatment strategies

Y Rodríguez-Santiago, CA Garay-Canales… - Biology of Sex …, 2024 - Springer
Introduction Sexual dimorphism significantly influences cancer incidence and prognosis.
Notably, females exhibit a lower risk and favorable prognosis for non-reproductive cancers …

Cholinergic Mechanisms in Gastrointestinal Neoplasia

N Sampaio Moura, A Schledwitz, M Alizadeh… - International Journal of …, 2024 - mdpi.com
Acetylcholine-activated receptors are divided broadly into two major structurally distinct
classes: ligand-gated ion channel nicotinic and G-protein-coupled muscarinic receptors …

Comprehensive pan‑cancer analysis of potassium voltage-gated channel Q4 (KCNQ4) gene across multiple human malignant tumors

Q Zhao, M Li, Y Zhang - Scientific Reports, 2023 - nature.com
A large number of studies indicate that Potassium Voltage-Gated Channel Q4 (KCNQ4)
gene is the cause of non-syndromic hearing loss, but there are few studies investigating the …

Neurotransmitter receptor-related gene signature as potential prognostic and therapeutic biomarkers in colorectal cancer

L Zhang, Y Deng, J Yang, W Deng, L Li - Frontiers in Cell and …, 2023 - frontiersin.org
Background: Colorectal cancer is one of the most common malignant tumors worldwide. A
various of neurotransmitter receptors have been found to be expressed in tumor cells, and …