The skeleton is a highly innervated organ in which nerve fibers interact with various skeletal
cells. Peripheral nerve endings release neurogenic factors and sense skeletal signals …

Innate and adaptive immune cells patrol and survey throughout the human body and
sometimes reside in the tumor microenvironment (TME) with a variety of cell types and …

Critical limb ischemia, the final course of peripheral artery disease, is characterized by an
insufficient supply of blood flow and excessive oxidative stress. H2S molecular therapy …

It remains challenging to cure chronic diabetic wounds due to its' harsh microenvironment
and poor tissue regeneration ability. At present, bacteria elimination, inflammatory response …

Pulmonary arterial hypertension forms the first and most severe of the 5 categories of
pulmonary hypertension. Disease pathogenesis is driven by progressive remodeling of …

BACKGROUND Abnormal uterine bleeding (AUB) has a significant socioeconomic impact
since it considerably impacts quality of life. Therapeutic options are frequently based on trial …

Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-associated death
worldwide. Angiogenesis, the process of formation of new blood vessels, is required for …

Wound repair, as one of the most intricate biological mechanisms, is essential to ensure the
formation and integrity of the skin barrier. However, multiple factors can cause delays and …

Cancer is a global intractable disease, and its morbidity and mortality are increasing year by
year in developing countries. Surgery and chemotherapy are often used to treat cancer, but …

The endothelial cells that compose the vascular system in the body display a wide range of
mechanotransductive behaviors and responses to biomechanical stimuli, which act in …