Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives

JE Choby, J Howard‐Anderson… - Journal of internal …, 2020 - Wiley Online Library
Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a concerning global
pathogen. hvKp is more virulent than classical K. pneumoniae (cKp) and capable of causing …

Antibiotic Resistance Related to Biofilm Formation in Klebsiella pneumoniae

C Vuotto, F Longo, MP Balice, G Donelli, PE Varaldo - Pathogens, 2014 - mdpi.com
The Gram-negative opportunistic pathogen, Klebsiella pneumoniae, is responsible for
causing a spectrum of community-acquired and nosocomial infections and typically infects …

[HTML][HTML] Identification of a novel plasmid-mediated colistin-resistance gene, mcr-2, in Escherichia coli, Belgium, June 2016

BB Xavier, C Lammens, R Ruhal… - …, 2016 - eurosurveillance.org
We identified a novel plasmid-mediated colistin-resistance gene in porcine and bovine
colistin-resistant Escherichia coli that did not contain mcr-1. The gene, termed mcr-2, a 1,617 …

Diversity and Function of Capsular Polysaccharide in Acinetobacter baumannii

JK Singh, FG Adams, MH Brown - Frontiers in microbiology, 2019 - frontiersin.org
The Gram-negative opportunistic bacterium Acinetobacter baumannii is a significant cause
of hospital-borne infections worldwide. Alarmingly, the rapid development of antimicrobial …

The making of hypervirulent Klebsiella pneumoniae

P Dai, D Hu - Journal of Clinical Laboratory Analysis, 2022 - Wiley Online Library
Klebsiella pneumoniae is a notorious bacterium in clinical practice. Virulence, carbapenem‐
resistance and their convergence among K. pneumoniae are extensively discussed in this …

Genome-wide identification of Klebsiella pneumoniae fitness genes during lung infection

MA Bachman, P Breen, V Deornellas, Q Mu, L Zhao… - MBio, 2015 - Am Soc Microbiol
Klebsiella pneumoniae is an urgent public health threat because of resistance to
carbapenems, antibiotics of last resort against Gram-negative bacterial infections. Despite …

RNA interactome of hypervirulent Klebsiella pneumoniae reveals a small RNA inhibitor of capsular mucoviscosity and virulence

K Wu, X Lin, Y Lu, R Dong, H Jiang… - Nature …, 2024 - nature.com
Abstract Hypervirulent Klebsiella pneumoniae (HvKP) is an emerging bacterial pathogen
causing invasive infection in immune-competent humans. The hypervirulence is strongly …

Klebsiella pneumoniae AI-2 transporters mediate interspecies interactions and composition in a three-species biofilm community

MZ Bin Mohammad Muzaki, S Subramoni… - npj Biofilms and …, 2024 - nature.com
Biofilms in nature often exist as communities. In this study, an experimental mixed-species
community consisting of Pseudomonas aeruginosa, Pseudomonas protegens and …

Dietary carbohydrates regulate intestinal colonization and dissemination of Klebsiella pneumoniae

AL Hecht, LC Harling, ES Friedman… - The Journal of …, 2024 - Am Soc Clin Investig
Bacterial translocation from the gut microbiota is a source of sepsis in susceptible patients.
Previous work suggests that overgrowth of gut pathobionts, including Klebsiella …

Opposite evolution of pathogenicity driven by in vivo wzc and wcaJ mutations in ST11-KL64 carbapenem-resistant Klebsiella pneumoniae

J He, Q Shi, Z Chen, W Zhang, P Lan, Q Xu, H Hu… - Drug Resistance …, 2023 - Elsevier
Aims To investigate the in vivo evolution of the mucoid-phenotype of ST11-KL64
carbapenem-resistant Klebsiella pneumoniae (CRKP) isolated from the same patients and …