ZnCl2:2HOAc: a deep eutectic solvent for the Friedel–Crafts acetylation of poly-phenols and chemo-selective protection of alcohols

F Tamaddon, H Rashidi - Research on Chemical Intermediates, 2023 - Springer
Deep eutectics (DEs) are golden alternatives for conventional solvents, catalysts, and
reagents. The present work focuses on a DE-acetylating agent from the screening of ZnCl2 …

Friedel–Crafts fluoroacetylation of indoles with fluorinated acetic acids for the synthesis of fluoromethyl indol-3-yl ketones under catalyst-and additive-free conditions

SJ Yao, ZH Ren, YY Wang… - The Journal of Organic …, 2016 - ACS Publications
A simple and efficient protocol for the fluoroacetylation of indoles is reported. The reaction
uses fluorinated acetic acids as the fluoroacetylation reagents to synthesize diverse …

Photo-Fries rearrangement in flow under aqueous micellar conditions

CC Chien, SC Kao, CJ Chen, YK Wu - Chemical Communications, 2020 - pubs.rsc.org
A flow edition of photo-Fries rearrangement for the synthesis of 2-acylphenols in an aqueous
micellar medium has been described. We take advantage of a narrow channel reactor and …

Versatile Biaryls and Fused Aromatics through Oxidative Coupling of Hydroquinones with (Hetero) Arenes

T Aijima, R Ueda, T Nakane, F Makino… - …, 2024 - Wiley Online Library
Hydroquinones bearing an electron‐withdrawing group at the C2‐position can effectively
underwent oxidative coupling with (hetero) arenes (eg, indoles, electron‐rich benzene …

Reusable Palladium Nanoparticles Catalyzed Oxime Ether Directed Mono Ortho‐Hydroxylation under Phosphine Free Neutral Condition

R Saha, N Perveen, N Nihesh… - Advanced Synthesis & …, 2019 - Wiley Online Library
An efficient, reusable and stable binaphthyl stabilized Pd‐nanoparticles (Pd‐BNP) catalyzed
the direct ortho‐C− H hydroxylation of acetophenone oxime ethers under neutral and …

Dinuclear versus mononuclear pathways in zinc mediated nucleophilic addition: a combined experimental and DFT study

X Qi, Y Li, G Zhang, Y Li, A Lei, C Liu, Y Lan - Dalton transactions, 2015 - pubs.rsc.org
Employing the oxidative coupling of phenylacetylene with benzaldehyde as a model
reaction, a density functional theory (DFT) study combined with extended X-ray absorption …

Some novel [6-(isoxazol-5-ylmethoxy)-3-methylbenzofuran-2-yl] phenylmethanone derivatives, their antimicrobial activity, and molecular docking studies on COVID-19

N Umapathi, B Shankar, M Raghavender… - Russian Journal of …, 2021 - Springer
A novel series of benzofuran-isoxazole hybrid heterocyclic unit has been synthesized and
their structures characterized by 1H and 13C NMR, and mass spectral data. The synthesized …

Towards ortho-selective electrophilic substitution/addition to phenolates in anhydrous solvents

E Lopušanskaja, A Kooli, A Paju, I Järving, M Lopp - Tetrahedron, 2021 - Elsevier
Alkyl-substituted Li-phenolates with BnBr in water solution lead to a mixture of o-and p-Bn-
substituted phenols together with a substantial amount of phenol Bn ether. In CPME, and …

Discovery of 2, 4-diarylaminopyrimidines bearing a resorcinol motif as novel ALK inhibitors to overcome the G1202R resistant mutation

K Geng, Z Xia, Y Ji, RR Zhang, D Sun, J Ai… - European Journal of …, 2018 - Elsevier
To address drug resistance caused by ALK kinase mutations, especially the most refractory
and predominant mutation G1202R for the second-generation ALK inhibitor, a series of new …

Efficient synthesis of 2, 4, 5-tri substituted imidazoles catalyzed by an ionic liquid derived from hexamine and 1, 4-butane sultone under solvent-free conditions

D Aghaseyedkarimi, H Naeimi - Journal of Molecular Structure, 2025 - Elsevier
Abstract The HMTA-[(CH 2) 4-SO 3 H] 4 4+(HSO 4−) 4 ionic liquid derived from
hexamethylene-tetramine and 1, 4-butane sultone was applied as an efficient and effective …