Recent advances in culture medium design for enhanced production of monoclonal antibodies in CHO cells: A comparative study of machine learning and systems …

H Kavoni, ISP Savizi, NE Lewis… - Biotechnology Advances, 2024 - Elsevier
The production of monoclonal antibodies (mAbs) using Chinese Hamster Ovary (CHO) cells
has revolutionized the treatment of numerous diseases, solidifying their position as a …

[HTML][HTML] Process control of mAb production using multi-actor proximal policy optimization

N Gupta, S Anand, T Joshi, D Kumar… - Digital Chemical …, 2023 - Elsevier
Monoclonal antibodies (mAb) are biopharmaceutical products that improve human
immunity. In this work, we propose a multi-actor proximal policy optimization-based …