Positive controls in adults and children support that very few, if any, new neurons are born in the adult human hippocampus

SF Sorrells, MF Paredes, Z Zhang, G Kang… - Journal of …, 2021 - Soc Neuroscience
Adult hippocampal neurogenesis was originally discovered in rodents. Subsequent studies
identified the adult neural stem cells and found important links between adult neurogenesis …

Markers of liver regeneration—the role of growth factors and cytokines: a systematic review

K Hoffmann, AJ Nagel, K Tanabe, J Fuchs, K Dehlke… - BMC surgery, 2020 - Springer
Background Post-hepatectomy liver failure contributes significantly to postoperative mortality
after liver resection. The prediction of the individual risk for liver failure is challenging. This …

Human hippocampal neurogenesis persists in aged adults and Alzheimer's disease patients

MK Tobin, K Musaraca, A Disouky, A Shetti, A Bheri… - Cell stem cell, 2019 - cell.com
Whether hippocampal neurogenesis persists throughout life in the human brain is not fully
resolved. Here, we demonstrate that hippocampal neurogenesis is persistent through the …

[HTML][HTML] Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes

JR Lin, B Izar, S Wang, C Yapp, S Mei, PM Shah… - elife, 2018 - elifesciences.org
The architecture of normal and diseased tissues strongly influences the development and
progression of disease as well as responsiveness and resistance to therapy. We describe a …

[HTML][HTML] A topographic atlas defines developmental origins of cell heterogeneity in the human embryonic lung

A Sountoulidis, S Marco Salas, E Braun, C Avenel… - Nature Cell …, 2023 - nature.com
The lung contains numerous specialized cell types with distinct roles in tissue function and
integrity. To clarify the origins and mechanisms generating cell heterogeneity, we created a …

Combining crocin and sorafenib improves their tumor-inhibiting effects in a rat model of diethylnitrosamine-induced cirrhotic-hepatocellular carcinoma

B Awad, AA Hamza, A Al-Maktoum, S Al-Salam, A Amin - Cancers, 2023 - mdpi.com
Simple Summary Liver cancer represents one of the most lethal forms of cancer, with
hepatocellular carcinoma (HCC) accounting for the majority of its incidences and deaths …

Identification of chemotherapy-induced leukemic-regenerating cells reveals a transient vulnerability of human AML recurrence

AL Boyd, L Aslostovar, J Reid, W Ye, B Tanasijevic… - Cancer cell, 2018 - cell.com
Despite successful remission induction, recurrence of acute myeloid leukemia (AML)
remains a clinical obstacle thought to be caused by the retention of dormant leukemic stem …

An assessment of the existence of adult neurogenesis in humans and value of its rodent models for neuropsychiatric diseases

A Duque, JI Arellano, P Rakic - Molecular psychiatry, 2022 - nature.com
In sub-mammalian vertebrates like fishes, amphibians, and reptiles, new neurons are
produced during the entire lifespan. This capacity diminishes considerably in birds and even …

Immunotherapy of cytomegalovirus infection by low-dose adoptive transfer of antiviral CD8 T cells relies on substantial post-transfer expansion of central memory cells …

R Holtappels, S Becker, S Hamdan, K Freitag… - PLoS …, 2023 - journals.plos.org
Cytomegaloviruses (CMVs) are host species-specific in their replication. It is a hallmark of all
CMVs that productive primary infection is controlled by concerted innate and adaptive …

Immunohistochemical expression of K6, K8, K16, K17, K19, maspin, syndecan-1 (CD138), α-SMA, and Ki-67 in ameloblastoma and ameloblastic carcinoma …

RA Safadi, BF Quda, HM Hammad - Oral Surgery, Oral Medicine, Oral …, 2016 - Elsevier
Objective To identify cutoff values of markers that correlate with the histopathologic
diagnosis of ameloblastic carcinoma (AC) and/or the increased recurrence potential of …