Targeting the inflammatory hallmarks of obesity-associated osteoarthritis: Towards nutraceutical-oriented preventive and complementary therapeutic strategies based …
Obesity (Ob), which has dramatically increased in the last decade, is one of the main risk
factors that contribute to the incidence and progression of osteoarthritis (OA). Targeting the …
factors that contribute to the incidence and progression of osteoarthritis (OA). Targeting the …
Molecular Foundations of Inflammatory Diseases: Insights into Inflammation and Inflammasomes
ME Kim, JS Lee - Current Issues in Molecular Biology, 2024 - mdpi.com
Inflammatory diseases are a global health problem affecting millions of people with a wide
range of conditions. These diseases, including inflammatory bowel disease (IBD) …
range of conditions. These diseases, including inflammatory bowel disease (IBD) …
Deferoxamine alleviates chondrocyte senescence and osteoarthritis progression by maintaining iron homeostasis
Z Guo, Y Lin, H Liu, J Guo, L Hou, X Zhang, J Xu… - International …, 2024 - Elsevier
Background Osteoarthritis (OA) is a prevalent age-related disease characterized by the
gradual deterioration of cartilage. The involvement of chondrocyte senescence is crucial in …
gradual deterioration of cartilage. The involvement of chondrocyte senescence is crucial in …
[HTML][HTML] Significance of Necroptosis in Cartilage Degeneration
Cartilage, a critical tissue for joint function, often degenerates due to osteoarthritis (OA),
rheumatoid arthritis (RA), and trauma. Recent research underscores necroptosis, a …
rheumatoid arthritis (RA), and trauma. Recent research underscores necroptosis, a …
(Chemical) Roles of HOCl in Rheumatic Diseases
J Leopold, J Schiller - Antioxidants, 2024 - pmc.ncbi.nlm.nih.gov
Chronic rheumatic diseases such as rheumatoid arthritis (RA) are characterized by a
dysregulated immune response and persistent inflammation. The large number of …
dysregulated immune response and persistent inflammation. The large number of …
Loss of collagen content is localized near cartilage lesions on the day of injurious loading and intensified on day 12
Joint injury can lead to articular cartilage damage, excessive inflammation, and post‐
traumatic osteoarthritis (PTOA). Collagen is an essential component for cartilage function …
traumatic osteoarthritis (PTOA). Collagen is an essential component for cartilage function …
Relationship between autophagy and NLRP3 inflammasome during articular cartilage degradation in oestrogen-deficient rats with streptozotocin-induced diabetes
R Florencio-Silva, GR da Silva Sasso… - Annals of Anatomy …, 2025 - Elsevier
Abstract Background Estrogen deficiency and Diabetes mellitus (DM) cause joint tissue
deterioration, although the mechanisms are uncertain. This study evaluated the …
deterioration, although the mechanisms are uncertain. This study evaluated the …
COL3A1 is a potential diagnostic biomarker for synovial chondromatosis and affects the cell cycle and migration of chondrocytes
WK Chen, HJ Zhang, Z Dai, XL Zhan - International …, 2024 - Elsevier
Background Synovial chondromatosis (SC) primarily affects the major joints and is
characterized by the formation of benign cartilaginous nodules. In the present study, we …
characterized by the formation of benign cartilaginous nodules. In the present study, we …
An automated and robust tool for musculoskeletal and finite element modeling of the knee joint
: To develop and assess an automatic and robust knee musculoskeletal finite element (MSK-
FE) modeling pipeline. Methods: Magnetic resonance images (MRIs) were used to train nnU …
FE) modeling pipeline. Methods: Magnetic resonance images (MRIs) were used to train nnU …
机械应力调控Hippo 通路影响骨关节炎的发生与发展
杨攀， 董万涛， 刘静怡， 邱世明， 袁鹏 - 中国组织工程研究, 2024 - cjter.com
机械应力调控Hippo 通路影响骨关节炎的发生与发展 Page 1 4902|中国组织工程研究|第28卷|第
30期|2024年10月 中国组织工程研究 Chinese Journal of Tissue Engineering Research www.CJTER.com …
30期|2024年10月 中国组织工程研究 Chinese Journal of Tissue Engineering Research www.CJTER.com …