Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment

HF Escobar-Morreale - Nature Reviews Endocrinology, 2018 - nature.com
Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic
disorders in premenopausal women. Heterogeneous by nature, PCOS is defined by a …

Obesity, polycystic ovary syndrome, and infertility: a new avenue for GLP-1 receptor agonists

H Cena, L Chiovato, RE Nappi - The Journal of Clinical …, 2020 - academic.oup.com
Context Obesity is responsible for an increased risk of sub-fecundity and infertility. Obese
women show poorer reproductive outcomes regardless of the mode of conception, and …

Characteristics of obesity in polycystic ovary syndrome: Etiology, treatment, and genetics

CJ Glueck, N Goldenberg - Metabolism, 2019 - Elsevier
Polycystic ovary syndrome (PCOS) has multiple etiologies including ovarian and adrenal
hyperandrogenism, neuro-endocrine and hypothalamic-pituitary dysfunction, and disorders …

The role of glp-1 receptor agonists in insulin resistance with concomitant obesity treatment in polycystic ovary syndrome

K Bednarz, K Kowalczyk, M Cwynar, D Czapla… - International journal of …, 2022 - mdpi.com
Insulin resistance is documented in clamp studies in 75% of women with polycystic ovary
syndrome (PCOS). Although it is not included in the diagnostic criteria of PCOS, there is a …

Polycystic ovary syndrome, adipose tissue and metabolic syndrome

AP Delitala, G Capobianco, G Delitala… - Archives of gynecology …, 2017 - Springer
Purpose Polycystic ovary syndrome (PCOS) is the most common endocrine disorder that
affects women of reproductive age and is characterized by ovulatory dysfunction and/or …

A review of therapeutic options for managing the metabolic aspects of polycystic ovary syndrome

MA Abdalla, H Deshmukh, S Atkin… - … in endocrinology and …, 2020 - journals.sagepub.com
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of
reproductive age. Metabolic sequelae associated with PCOS range from insulin resistance …

Effect of liraglutide on ectopic fat in polycystic ovary syndrome: a randomized clinical trial

S Frøssing, M Nylander, E Chabanova… - Diabetes, Obesity …, 2018 - Wiley Online Library
Women with polycystic ovary syndrome (PCOS) were treated with the GLP‐1 receptor
agonist liraglutide to investigate the effect on liver fat content, visceral adipose tissue (VAT) …

GLP-1 receptor agonists versus metformin in PCOS: a systematic review and meta-analysis

Y Han, Y Li, B He - Reproductive biomedicine online, 2019 - Elsevier
This meta-analysis aimed to evaluate the efficacy and safety of glucagon-like peptide 1 (GLP-
1) receptor agonists for women with polycystic ovary syndrome (PCOS) by comparing their …

Insulin sensitizers for improving the endocrine and metabolic profile in overweight women with PCOS

C Xing, C Li, B He - The Journal of Clinical Endocrinology & …, 2020 - academic.oup.com
Objective To evaluate the efficacy of insulin sensitizers on menstrual frequency, sex
hormone, and metabolic parameters in overweight women with polycystic ovary syndrome …

The role of glucagon-like peptide-1 in reproduction: from physiology to therapeutic perspective

M Jensterle, A Janez, E Fliers… - Human reproduction …, 2019 - academic.oup.com
Abstract BACKGROUND Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1 RAs)
have become firmly established in the treatment of type 2 diabetes and obesity, disorders …