Biocatalytic reduction reactions from a chemist's perspective

F Hollmann, DJ Opperman… - Angewandte Chemie …, 2021 - Wiley Online Library
Reductions play a key role in organic synthesis, producing chiral products with new
functionalities. Enzymes can catalyse such reactions with exquisite stereo‐, regio‐and …

Recent trends and novel concepts in cofactor-dependent biotransformations

S Kara, JH Schrittwieser, F Hollmann… - Applied microbiology …, 2014 - Springer
Cofactor-dependent enzymes catalyze a broad range of synthetically useful transformations.
However, the cofactor requirement also poses economic and practical challenges for the …

Cofactor NAD (P) H regeneration inspired by heterogeneous pathways

X Wang, T Saba, HHP Yiu, RF Howe, JA Anderson… - Chem, 2017 - cell.com
Biocatalysis can empower chemical, pharmaceutical, and energy industries, where the use
of enzymes facilitates low-energy, sustainable methods of producing high-value chemicals …

[PDF][PDF] How Green is Biocatalysis? To Calculate is To Know.

Y Ni, D Holtmann, F Hollmann - ChemCatChem, 2014 - researchgate.net
Green chemistry aims to minimize the environmental hazards of chemical processes and
their products. Ever since its introduction by Anastas,[1] this principle has inspired …

Biocatalysis

G Torrelo, U Hanefeld, F Hollmann - Catalysis Letters, 2015 - Springer
Biocatalysis is an enabling technology for chemists. Using isolated enzymes or whole cells
gives access to a broad range of selective transformations—often inaccessible with …

H2‐driven cofactor regeneration with NAD(P)+‐reducing hydrogenases

L Lauterbach, O Lenz, KA Vincent - The FEBS journal, 2013 - Wiley Online Library
A large number of industrially relevant enzymes depend upon nicotinamide cofactors, which
are too expensive to be added in stoichiometric amounts. Existing NAD (P) H‐recycling …

A biocatalytic hydrogenation of carboxylic acids

Y Ni, PL Hagedoorn, JH Xu, IWCE Arends… - Chemical …, 2012 - pubs.rsc.org
The hyperthermophile Pyrococcus furiosus catalyses the hydrogenation of a broad range of
carboxylic acids selectively to the corresponding primary alcohols. Other functional groups …

[PDF][PDF] Enzymatic processes in alternative reaction media: a mini review

M Ghaffari-Moghaddam, H Eslahi… - Journal of Biological …, 2015 - scholar.archive.org
Biocatalysis is a growing field in the production of fine chemicals and will most probably
increase its share in the future. Enzymatic reactions are carried out under mild conditions, ie …

The [NiFe]-Hydrogenase of Pyrococcus furiosus Exhibits a New Type of Oxygen Tolerance

P Kwan, CL McIntosh, DP Jennings… - Journal of the …, 2015 - ACS Publications
We report the first direct electrochemical characterization of the impact of oxygen on the
hydrogen oxidation activity of an oxygen-tolerant, group 3, soluble [NiFe]-hydrogenase …

Enzymatically crosslinked dendritic polyglycerol nanogels for encapsulation of catalytically active proteins

C Wu, C Böttcher, R Haag - Soft Matter, 2015 - pubs.rsc.org
The enormous potential of nanogel scaffolds for protein encapsulation has been widely
recognized. However, constructing stable polymeric nanoscale networks in a facile, mild …