Inflammation plays an important role in the pathogenesis of ischemic stroke and other forms
of ischemic brain injury. Increasing evidence suggests that inflammatory response is a …

Thiosulfate in the form of sodium thiosulfate (STS) is a major oxidation product of hydrogen
sulfide (H2S), an endogenous signaling molecule and the third member of the …

Chronic inflammation is characterized by longstanding microglial activation followed by
sustained release of inflammatory mediators, which aid in enhanced nitrosative and …

Background Dendritic cell-associated C-type lectin-1 (Dectin-1) receptor has been reported
to be involved in neuroinflammation in Alzheimer's disease and traumatic brain injury. The …

Aims Adipocyte fatty acid-binding protein (A-FABP) is an adipokine implicating in various
metabolic diseases. Elevated circulating levels of A-FABP correlate positively with poor …

Background Mitogen-activated protein kinase (MAPK) signaling pathways are implicated in
inflammatory and apoptotic processes of cerebral ischemia and reperfusion (I/R) injury …

Much evidence demonstrated that autophagy played an important role in neural
inflammation response after ischemia stroke. However, the specific effect of microglia …

Background Emerging evidence indicates that reactive microglia-initiated inflammatory
responses are responsible for secondary damage after primary traumatic spinal cord injury …

Background: Lactate protects mice against the ischaemic damage resulting from transient
middle cerebral artery occlusion (MCAO) when administered intracerebroventricularly at …

Background Hydrogen sulfide (H2S) exhibits protective effects in various disease models
including cerebral ischemia–reperfusion (I/R) injury. Nonetheless, mechanisms and identity …