Cartilage degeneration is among the fundamental reasons behind disability and pain across
the globe. Numerous approaches have been employed to treat cartilage diseases …

The osteochondral defect repair has been most extensively studied due to the rising
demand for new therapies to diseases such as osteoarthritis. Tissue engineering has been …

The use of tissue-engineered articular cartilage (TEAC) constructs has the potential to
become a powerful treatment option for cartilage lesions resulting from trauma or early …

The aim of osteochondral tissue engineering is to achieve the complex, functional and three-
dimensional tissue regeneration under well defined, controlled and reproducible conditions …

In this review, we discuss the interaction of mechanical factors influencing knee
osteoarthritis (KOA) and post-traumatic osteoarthritis (PTOA) pathogenesis. Emphasizing the …

Articular cartilage (AC) is the weight-bearing tissue in diarthroses. It lacks the capacity for
self-healing once there are injuries or diseases due to its avascularity. With the development …

Developmental engineering strategies aim to recapitulate aspects of development in vitro as
a means of forming functional engineered tissues, including cartilage and bone, for tissue …

Osteoarthritis (OA) is a degenerative disease characterised by articular cartilage destruction,
and its complex aetiology contributes to suboptimal clinical treatment outcomes. A close …

In this work a coupled model of solute transport and uptake, cell proliferation, extracellular
matrix synthesis and remodeling of mechanical properties accounting for the impact of …

Patients with cartilage damage have various discomforts, including pain, clicks, deformities,
and dysfunction. Chondrocytes are a crucial component of cartilage restoration; however …