Leptospirosis is a significant zoonosis worldwide, with disease severity ranging from a mild
non-specific illness to multi-organ dysfunction and hemorrhage. The disease is caused by …

Pathogenic spirochaetes of the genus Leptospira are the etiological agents of leptospirosis,
a zoonotic infection worldwide. The disease is considered an emerging and re-emerging …

Abstract The USDA/ARS-National Disease Center (NADC) will celebrate its 65th
anniversary of existence in November 2026. NADC continues as one of the world's premier …

Introduction Leptospirosis is a worldwide zoonosis caused by pathogenic and virulent
species of the genus Leptospira, whose pathophysiology and virulence factors remain …

Leptospirosis, caused by pathogenic bacteria from the genus Leptospira, is a global
zoonosis responsible for more than one million human cases and 60,000 deaths annually …

The genus Leptospira is a diverse and unique group of bacteria comprising multiple
saprophytic and pathogenic species, which survive and persist in suitable moist …

In the last 20 years, various research groups have endeavored to develop recombinant
vaccines against leptospirosis to overcome the limitations of commercially available …

Bacterial immunoglobulin-like (BIg) domain containing proteins play a variety of biological
functions. Leptospiral Immunoglobulin-like (Lig) proteins are well-known virulence factors …

Leptospirosis is a global zoonosis caused by pathogenic bacteria of the genus Leptospira.
The application of the CRISPR/Cas9 system has facilitated the generation of mutants and …

Leptospirosis is of general concern as it is a widespread zoonotic disease caused by
pathogenic species of the genus Leptospira, although this genus also includes free-living …