The metabolic domestication syndrome of budding yeast
R Tengölics, B Szappanos… - Proceedings of the …, 2024 - National Acad Sciences
Cellular metabolism evolves through changes in the structure and quantitative states of
metabolic networks. Here, we explore the evolutionary dynamics of metabolic states by …
metabolic networks. Here, we explore the evolutionary dynamics of metabolic states by …
Cross-species modeling of muscular dystrophy in Caenorhabditis elegans using patient-derived extracellular vesicles
R Shalash, M Levi-Ferber, C Cohen… - Disease Models & …, 2024 - journals.biologists.com
Reliable disease models are critical for medicine advancement. Here, we established a
versatile human disease model system using patient-derived extracellular vesicles (EVs) …
versatile human disease model system using patient-derived extracellular vesicles (EVs) …
Widespread natural selection on metabolite levels in humans
Natural selection acts ubiquitously on complex human traits, predominantly constraining the
occurrence of extreme phenotypes (stabilizing selection). These constraints propagate to …
occurrence of extreme phenotypes (stabilizing selection). These constraints propagate to …