Ambient ionization and miniature mass spectrometry system for chemical and biological analysis

X Ma, Z Ouyang - TrAC Trends in Analytical Chemistry, 2016 - Elsevier
Ambien ionization and miniaturization of mass spectrometers are two fields in mass
spectrometry that have advanced significantly in the last decade. The integration of the …

Recent progress in small spirocyclic, xanthene-based fluorescent probes

S G. Keller, M Kamiya, Y Urano - Molecules, 2020 - mdpi.com
The use of fluorescent probes in a multitude of applications is still an expanding field. This
review covers the recent progress made in small molecular, spirocyclic xanthene-based …

Modular Design Platform for Activatable Fluorescence Probes Targeting Carboxypeptidases Based on ProTide Chemistry

Y Kuriki, M Sogawa, T Komatsu… - Journal of the …, 2023 - ACS Publications
Carboxypeptidases (CPs) are a family of hydrolases that cleave one or more amino acids
from the C-terminal of peptides or proteins and play indispensable roles in various …

Screening of exosome-derived proteins and their potential as biomarkers in diagnostic and prognostic for pancreatic cancer

AM Marin, M Batista, AL Korte de Azevedo… - International Journal of …, 2023 - mdpi.com
In the oncological area, pancreatic cancer is one of the most lethal diseases, with 5-year
survival rising just 10% in high-development countries. This disease is genetically …

Establishment of molecular design strategy to obtain activatable fluorescent probes for carboxypeptidases

Y Kuriki, M Kamiya, H Kubo, T Komatsu… - Journal of the …, 2018 - ACS Publications
Carboxypeptidases (CPs) are a family of hydrolases that cleave one or more amino acids
from the C-terminal of peptides or proteins. However, methodology to monitor the activities of …

Electrochemical detection of protein based on hybridization chain reaction-assisted formation of copper nanoparticles

J Zhao, S Hu, Y Cao, B Zhang, G Li - Biosensors and Bioelectronics, 2015 - Elsevier
In this paper, we report an electrochemical method for highly sensitive and specific detection
of protein based on hybridization chain reaction (HCR)-assisted formation of copper …

Discovering breast cancer biomarkers candidates through mRNA expression analysis based on the cancer genome atlas database

DH Kim, KE Lee - Journal of Personalized Medicine, 2022 - mdpi.com
Background: Research on the discovery of tumor biomarkers based on big data analysis is
actively being conducted. This study aimed to secure foundational data for identifying new …

Visible to mid IR: A library of multispectral diagnostic imaging

M Won, M Li, HS Kim, P Liu, S Koo, S Son… - Coordination Chemistry …, 2021 - Elsevier
Fluorescence imaging is an essential and interdisciplinary optical technique that uses light
signals from molecules, cells, and living organisms to visualize dynamic biological …

Carboxypeptidase N1 is anticipated to be a synergy metrics for chemotherapy effectiveness and prognostic significance in invasive breast cancer

R Cui, C Wang, T Li, J Hua, T Zhao, L Ren… - Cancer Cell …, 2021 - Springer
Background The incidence and mortality of invasive breast cancer (IBC) are increasing
annually. Hence, it is urgently needed to determine reliable biomarkers for not only …

Plasma degradome affected by variable storage of human blood

M Kaisar, LFA Van Dullemen, ML Thézénas… - Clinical proteomics, 2016 - Springer
Background The successful application of—omics technologies in the discovery of novel
biomarkers and targets of therapeutic interventions is facilitated by large collections of well …