The transition from normal to chronic pain is believed to involve alterations in several brain
areas that participate in the perception of pain. These plastic changes are then responsible …

Social behaviors, how individuals act cooperatively and competitively with conspecifics, are
widely seen across species. Rodents display various social behaviors, and many different …

The Insula functions as a multisensory relay involved in socio-emotional processing with
projections to sensory, cognitive, emotional, and motivational regions. Notably, the …

Dravet syndrome (DS) is a severe neurodevelopmental disorder caused by loss-of-function
variants in SCN1A, which encodes the voltage-gated sodium channel subunit Nav1. 1. We …

The subiculum, a key output region of the hippocampus, is increasingly recognized as
playing a crucial role in seizure initiation and spread. The subiculum consists of …

Methamphetamine use disorder (MUD) is a neuropsychiatric disorder characterized by
binge drug taking episodes, intervals of abstinence, and relapses to drug use even during …

To accurately explore the anatomical organization of neural circuits in the brain, it is crucial
to map the experimental brain data onto a standardized system of coordinates. Studying 2D …

Pain-related aversive memory is common in chronic pain patients. Electroacupuncture has
been demonstrated to block pain-related aversive memory. The insular cortex is a key …

Trigeminal neuropathic pain (TNP) is a major concern in both dentistry and medicine. The
progression from normal to chronic TNP through activation of the insular cortex (IC) is …

The insula plays a significant role in the neural mechanisms of obsessive-compulsive
disorder. Previous studies have identified functional and structural abnormalities in insula in …