The mammalian nervous system is comprised of a seemingly infinitely complex network of
specialized synaptic connections that coordinate the flow of information through it. The field …

It has become widely appreciated that the spinal cord has significant neuroplastic potential,
is not hard-wired, and that with traumatic injury and anatomical plasticity, the networks that …

Regulation of systemic PCO 2 is a life-preserving homeostatic mechanism. In the medulla
oblongata, the retrotrapezoid nucleus (RTN) and rostral medullary Raphe are proposed as …

Targeting individual neurons in vivo is a key method to study the role of single cell types
within local and brain-wide microcircuits. While novel technological developments now …

Single-cell characterization and perturbation of neurons provides knowledge critical to
addressing fundamental neuroscience questions including the structure–function …

Hippocampal pyramidal neurons exhibit diverse spike patterns and gene expression
profiles. However, their relationships with single neurons are not fully understood. In this …

Cholinergic signaling is essential to mediate the auditory prepulse inhibition (PPI), an
operational measure of sensorimotor gating, that refers to the reduction of the acoustic …

Neurons generate various spike patterns to execute different functions. Understanding how
these physiological neuronal spike patterns are related to their molecular characteristics is a …

Aim Selective chemogenetic modulation of locus coeruleus (LC) neurons would allow
dedicated investigation of the role of the LC-NA pathway in brain excitability and disorders …

Background Exogenous gene introduction by transfection is one of the most important
approaches for understanding the function of specific genes at the cellular level …