Amyloid beta in aging and Alzheimer's disease

U Sehar, P Rawat, AP Reddy, J Kopel… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD), is a progressive neurodegenerative disease that affects behavior,
thinking, learning, and memory in elderly individuals. AD occurs in two forms, early onset …

[HTML][HTML] The impact of aerobic and resistance training intensity on markers of neuroplasticity in health and disease

T Hortobágyi, T Vetrovsky, GM Balbim… - Ageing Research …, 2022 - Elsevier
Objective To determine the effects of low-vs. high-intensity aerobic and resistance training
on motor and cognitive function, brain activation, brain structure, and neurochemical …

FNDC5/Irisin system in neuroinflammation and neurodegenerative diseases: update and novel perspective

P Pignataro, M Dicarlo, R Zerlotin, C Zecca… - International Journal of …, 2021 - mdpi.com
Irisin, the circulating peptide originating from fibronectin type III domain-containing protein 5
(FNDC5), is mainly expressed by muscle fibers under peroxisome proliferator-activated …

Protective actions of exercise‐related FNDC5/Irisin in memory and Alzheimer's disease

GB de Freitas, MV Lourenco… - Journal of …, 2020 - Wiley Online Library
The proportion of elderly populations is rapidly booming, and human lifespan has
considerably increased in the past century because of scientific and medical advances …

Activity-dependent transcriptional programs in memory regulate motor recovery after stroke

MT Joy, ST Carmichael - Communications Biology, 2024 - nature.com
Stroke causes death of brain tissue leading to long-term deficits. Behavioral evidence from
neurorehabilitative therapies suggest learning-induced neuroplasticity can lead to beneficial …

Sperm DNA methylation alterations from cannabis extract exposure are evident in offspring

R Schrott, JL Modliszewski, AB Hawkey… - Epigenetics & …, 2022 - Springer
Background Cannabis legalization is expanding and men are the predominant users. We
have limited knowledge about how cannabis impacts sperm and whether the effects are …

The emerging neuroprotective roles of exerkines in Alzheimer's disease

T Rody, JA De Amorim, FG De Felice - Frontiers in Aging …, 2022 - frontiersin.org
Despite the extensive knowledge of the beneficial effects of physical exercise, a sedentary
lifestyle is still a predominant harm in our society. Sedentarism is one of the major modifiable …

Dendritic spine initiation in brain development, learning and diseases and impact of BAR-domain proteins

P Khanal, P Hotulainen - Cells, 2021 - mdpi.com
Dendritic spines are small, bulbous protrusions along neuronal dendrites where most of the
excitatory synapses are located. Dendritic spine density in normal human brain increases …

Mechanical regulation of synapse formation and plasticity

T Minegishi, RF Kastian, N Inagaki - Seminars in Cell & Developmental …, 2023 - Elsevier
Dendritic spines are small protrusions arising from dendrites and constitute the major
compartment of excitatory post-synapses. They change in number, shape, and size …

Mechanisms underlying the effect of voluntary running on adult hippocampal neurogenesis

Y Gao, M Syed, X Zhao - Hippocampus, 2023 - Wiley Online Library
Adult hippocampal neurogenesis is important for preserving learning and memory‐related
cognitive functions. Physical exercise, especially voluntary running, is one of the strongest …