Introduction: The gastrointestinal mucosa constitutes a critical barrier where millions of
microbes and environmental antigens come in close contact with the host immune system …

Coeliac disease is a common disorder that can arise at any age and typically presents with a
broad spectrum of symptoms. The disease is thought to be underdiagnosed, in part owing to …

Background: Intestinal exposure to gliadin leads to zonulin upregulation and consequent
disassembly of intercellular tight junctions and increased intestinal permeability. We aimed …

The consumption of gluten-free products is becoming an increased alimentary habit in the
general population. The scientific unfounded perception suggesting that the avoidance of …

The connection between a dysregulated gut-associated lymphoid tissue and IgA
nephropathy (IgAN) was supposed decades ago after the observation of increased …

Celiac disease (CD) and type 1 diabetes (T1D) are autoimmune conditions in which dietary
gluten has been proven or suggested to play a pathogenic role. In CD; gluten is established …

Celiac disease (CD) is the most common autoimmune enteropathy worldwide. In CD, dietary
gluten triggers a T cell driven small intestinal inflammation in a subset of genetically …

Background: A growing number of individuals reports symptoms related to the ingestion of
gluten-containing food in the absence of celiac disease. Yet the actual prevalence is not well …

Celiac disease is characterized by intestinal inflammation triggered by gliadin, a component
of dietary gluten. Oral administration of proteases that can rapidly degrade gliadin in the …

Gluten-related disorders (GRD) affects approximately 10% of the general population. The
only treatment for GRD is still so far is the lifelong complete exclusion of gluten from the daily …