Chimeric antigen receptor-engineered natural killer cells for cancer immunotherapy
A Yilmaz, H Cui, MA Caligiuri, J Yu - Journal of hematology & oncology, 2020 - Springer
Natural killer (NK) cells are a critical component of the innate immune system. Chimeric
antigen receptors (CARs) re-direct NK cells toward tumor cells carrying corresponding …
antigen receptors (CARs) re-direct NK cells toward tumor cells carrying corresponding …
Platelet-mediated protection of cancer cells from immune surveillance–possible implications for cancer immunotherapy
The growing insights in the complex interactions between metastatic cancer-cells and
platelets have revealed that platelet tumor cell interactions in the blood stream are an …
platelets have revealed that platelet tumor cell interactions in the blood stream are an …
[HTML][HTML] Future of immune checkpoint inhibitors: focus on tumor immune microenvironment
Y Jia, L Liu, B Shan - Annals of Translational Medicine, 2020 - ncbi.nlm.nih.gov
Immunotherapy has become a powerful clinical strategy in cancer treatment. Immune
checkpoint inhibitors (ICIs) have opened a new era for cancer immunotherapy. Nowadays …
checkpoint inhibitors (ICIs) have opened a new era for cancer immunotherapy. Nowadays …
Manufacturing natural killer cells as medicinal products
Natural Killer (NK) cells are innate lymphoid cells (ILC) with cytotoxic and regulatory
properties. Their functions are tightly regulated by an array of inhibitory and activating …
properties. Their functions are tightly regulated by an array of inhibitory and activating …
Killer immunoglobulin-like receptor 2DL4 (Cd158d) regulates human mast cells both positively and negatively: Possible roles in pregnancy and cancer metastasis
TR Kataoka, C Ueshima, M Hirata… - International journal of …, 2020 - mdpi.com
Killer immunoglobulin-like receptor (KIR) 2DL4 (CD158d) was previously thought to be a
human NK cell-specific protein. Mast cells are involved in allergic reactions via their KIT …
human NK cell-specific protein. Mast cells are involved in allergic reactions via their KIT …
Delivery of a novel membrane-anchored Fc chimera enhances NK cell-mediated killing of tumor cells and persistently virus-infected cells
N Varudkar, EM Shiffer, JL Oyer, A Copik, GD Parks - Plos one, 2023 - journals.plos.org
Antibody-dependent cellular cytotoxicity (ADCC) is one of the most powerful mechanisms for
Natural Killer (NK) cells to kill cancer cells or virus-infected cells. A novel chimeric protein …
Natural Killer (NK) cells to kill cancer cells or virus-infected cells. A novel chimeric protein …
Clinical application of obinutuzumab for treating chronic lymphocytic leukemia
C Luan, B Chen - Drug Design, Development and Therapy, 2019 - Taylor & Francis
Alkylators and nucleoside analogs were the main drugs for treatingchronic lymphoblastic
leukemia (CLL), which have been replaced by monoclonal antibodies, such as rituximab in …
leukemia (CLL), which have been replaced by monoclonal antibodies, such as rituximab in …
Combination therapy with the type II anti-CD20 antibody obinutuzumab
Introduction: Obinutuzumab is a novel humanized type II glycoengineered anti-CD20
antibody approved for first-line treatment of chronic lymphocytic leukemia (CLL) in …
antibody approved for first-line treatment of chronic lymphocytic leukemia (CLL) in …
In vitro Untersuchung spenderspezifischer Unterschiede in der antileukämischen Lysefähigkeit von NK-Zellen gegenüber pädiatrischer B-Zell-Leukämien mit und …
FM Wiedenmann - 2020 - ub01.uni-tuebingen.de
Die akute lymphatische Leukämie (ALL) ist die häufigste Krebserkrankung im Kindesalter.
Von 2005 bis 2014 erkrankten in Deutschland im Mittel pro Jahr ca. 1.760 Kinder unter 15 …
Von 2005 bis 2014 erkrankten in Deutschland im Mittel pro Jahr ca. 1.760 Kinder unter 15 …