[HTML][HTML] ABC transporter-mediated MXR mechanism in fish embryos and its potential role in the efflux of nanoparticles

J Yin, J Hu, X Deng, Y Zheng, J Tian - Ecotoxicology and Environmental …, 2023 - Elsevier
ATP-binding cassette (ABC) transporters are believed to protect aquatic organisms by
pumping xenobiotics out, and recent investigation has suggested their involvement in the …

[HTML][HTML] Enhanced neurotoxic effect of PCB-153 when co-exposed with polystyrene nanoplastics in zebrafish larvae

S Varshney, MM Hegstad-Pettersen… - Chemosphere, 2024 - Elsevier
Nanoplastics (NPs) and persistent organic pollutants such as polychlorinated biphenyls
(PCBs) are ubiquitous aquatic pollutants. The coexistence of these pollutants in the …

TICBase: Integrated Resource for Data on Drug and Environmental Chemical Interactions with Mammalian Drug Transporters

ME Michel, CC Wen, SW Yee… - Clinical …, 2023 - Wiley Online Library
Environmental health science seeks to predict how environmental toxins, chemical toxicants,
and prescription drugs accumulate and interact within the body. Xenobiotic transporters of …

A Review of P-Glycoprotein Function and Regulation in Fish

CU Johnston, CJ Kennedy - Fishes, 2024 - mdpi.com
The teleost ATP Binding Cassette (ABC) transporter P-glycoprotein (P-gp) is an active
transmembrane transporter that plays a pivotal role in facilitating the movement of both …

Functional knockout of the Oatp1d1 membrane transporter affects toxicity of diclofenac in zebrafish embryos

L Vujica, I Mihaljević, J Dragojević, J Lončar, D Karaica… - Aquatic toxicology, 2024 - Elsevier
Organic anion transporting polypeptides (OATPs) facilitate the cellular uptake of a large
number of compounds. Zebrafish Oatp1d1 matches the functional capabilities of human …

[HTML][HTML] Exposure to virgin and marine incubated microparticles of biodegradable and conventional polymers modulates the hepatopancreas transcriptome of Mytilus …

G Limonta, C Panti, MC Fossi, F Nardi… - Journal of Hazardous …, 2024 - Elsevier
Biodegradable polymers have been proposed as an alternative to conventional plastics to
mitigate the impact of marine litter, but the research investigating their toxicity is still in its …

Abnormality of mussel in the early developmental stages induced by graphene and triphenyl phosphate: In silico toxicogenomic data-mining, in vivo, and toxicity …

X Wang, F Li, X Meng, C Xia, C Ji, H Wu - Aquatic Toxicology, 2023 - Elsevier
Increasing number of complex mixtures of organic pollutants in coastal area (especially for
nanomaterials and micro/nanoplastics associated chemicals) threaten aquatic ecosystems …

Function and regulation of P-glycoprotein in the liver of teleost fish

CU Johnston - 2024 - summit.sfu.ca
P-glycoptotein (P-gp), an active transmembrane exporter, transports various substances
across cell membranes, sharing a similar set of substrates with other transporters in a …

Maternal PCB Exposure Reprogrammed the Drug-processing Transcriptome of Testis in Mouse Offspring Over a Time Course

EM Jung - 2023 - search.proquest.com
Abstract Polychlorinated Biphenyls (PCBs) are persistent environmental contaminants that
pose a significant public health risk including reproductive toxicity partly because they are …

[图书][B] Analysis and Development of Database Resources for the Integration of Transporter Protein Research Across Biological Disciplines with an Emphasis on …

ME Michel - 2022 - search.proquest.com
Transmembrane transporter proteins facilitate an essential biological role in all living
organisms by regulating the movement of substances across lipid membranes. The ABC …