Recent progress in adjuvant discovery for peptide-based subunit vaccines

F Azmi, AAH Ahmad Fuaad… - Human vaccines & …, 2014 - Taylor & Francis
Peptide-based subunit vaccines are of great interest in modern immunotherapy as they are
safe, easy to produce and well defined. However, peptide antigens produce a relatively …

[HTML][HTML] Development of mucosal vaccine delivery: an overview on the mucosal vaccines and their adjuvants

R Anggraeni, ID Ana… - Clinical and Experimental …, 2022 - ncbi.nlm.nih.gov
Currently, mucosal infectious diseases are still a very high global health burden, but there
are few effective vaccines to prevent mucosal-borne diseases. The development of mucosal …

PET imaging of TREM1 identifies CNS-infiltrating myeloid cells in a mouse model of multiple sclerosis

AM Chaney, HC Cropper, P Jain, E Wilson… - Science translational …, 2023 - science.org
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous
system (CNS) that causes substantial morbidity and diminished quality of life. Evidence …

[HTML][HTML] Selection of adjuvants for enhanced vaccine potency

W Wang, M Singh - World Journal of Vaccines, 2011 - scirp.org
The advent of mass vaccination has saved millions of human lives and revolutionized the
quality of life. Vaccination is currently one of the most cost effective ways of managing …

[HTML][HTML] Peptide-based vaccines for neurodegenerative diseases: Recent endeavors and future perspectives

V Vassilakopoulou, CE Karachaliou, A Evangelou… - Vaccines, 2021 - mdpi.com
The development of peptide-based vaccines for treating human neurodegenerative
diseases has been the eventual aim of many research endeavors, although no active …

The Immunological Enhancement Activity of Propolis Flavonoids Liposome In Vitro and In Vivo

Y Tao, D Wang, Y Hu, Y Huang, Y Yu… - Evidence‐Based …, 2014 - Wiley Online Library
The aim of this study was to investigate and assess the effects of propolis flavonoids
liposome imposed on the immune system by comparing it to propolis flavonoids and blank …

[HTML][HTML] Potentiating effects of MPL on DSPC bearing cationic liposomes promote recombinant GP63 vaccine efficacy: high immunogenicity and protection

S Mazumder, M Maji, N Ali - PLoS neglected tropical diseases, 2011 - journals.plos.org
Background Vaccines that activate strong specific Th1-predominant immune responses are
critically needed for many intracellular pathogens, including Leishmania. The requirement …

[HTML][HTML] Comparison of BCG, MPL and cationic liposome adjuvant systems in leishmanial antigen vaccine formulations against murine visceral leishmaniasis

R Ravindran, S Bhowmick, A Das, N Ali - BMC microbiology, 2010 - Springer
Background The development of an effective vaccine against visceral leishmaniasis (VL)
caused by Leishmania donovani is an essential aim for controlling the disease. Use of the …

[HTML][HTML] Phytol-derived novel isoprenoid immunostimulants

RR Chowdhury, SK Ghosh - Frontiers in Immunology, 2012 - frontiersin.org
This review describes the adjuvanticity of novel diterpenoids (synthetic phytol derivatives)
compared to some commercially available adjuvants. The efficacy of the phytol-derived …

[HTML][HTML] The development of surface-modified liposomes as an intranasal delivery system for group a Streptococcus vaccines

J Yang, JC Boer, M Khongkow, S Phunpee, ZG Khalil… - Vaccines, 2023 - mdpi.com
Intranasal vaccine administration can overcome the disadvantages of injectable vaccines
and present greater efficiency for mass immunization. However, the development of …