Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder
affecting upper and lower motor neurons, with death resulting mainly from respiratory failure …

Bulbar dysfunction is a common presentation of amyotrophic lateral sclerosis (ALS) and
significantly impacts quality of life of people with ALS (PALS). The current paper reviews …

Objective The ALS Functional Rating Scale–Revised (ALSFRS-R) is the most commonly
utilized instrument to index bulbar function in both clinical and research settings. We …

Purpose The purpose of this article was to validate a novel acoustic analysis of oral
diadochokinesis (DDK) in assessing bulbar motor involvement in amyotrophic lateral …

Objective No efficacious treatments exist to improve or prolong bulbar functions of speech
and swallowing in persons with amyotrophic lateral sclerosis (pALS). This study evaluated …

Little is known regarding the optimal timing of dysphagia assessment and PEG indication in
amyotrophic lateral sclerosis (ALS). The study aims to investigate the progression of …

Purpose The purposes of this study are to develop a novel multimodal framework for
measuring variability at the muscular, kinematic, and acoustic levels of the motor speech …

Purpose The purpose of this research note is to provide a performance comparison of
available algorithms for the automated evaluation of oral diadochokinesis using speech …

Abstract Background and Objective: Bulbar dysfunction is a term used in amyotrophic lateral
sclerosis (ALS). It refers to motor neuron disability in the corticobulbar area of the brainstem …

Objectives This study aimed to systematically assess the quality of CPGs for motor neuron
diseases (MNDs) or related disorders and identify the gaps that limit evidence-based …