Electrical stimulation for the treatment of spinal cord injuries: A review of the cellular and molecular mechanisms that drive functional improvements

RM Dorrian, CF Berryman, A Lauto… - Frontiers in Cellular …, 2023 - frontiersin.org
Spinal cord injury (SCI) is a devastating condition that causes severe loss of motor, sensory
and autonomic functions. Additionally, many individuals experience chronic neuropathic …

Assessing neurogenic lower urinary tract dysfunction after spinal cord injury: Animal models in preclinical neuro-urology research

AW Doelman, F Streijger, SJA Majerus, MS Damaser… - Biomedicines, 2023 - mdpi.com
Neurogenic bladder dysfunction is a condition that affects both bladder storage and voiding
function and remains one of the leading causes of morbidity after spinal cord injury (SCI) …

Composite fibrin/carbon microfiber implants for bridging spinal cord injury: a translational approach in pigs

A Alves-Sampaio, P Del-Cerro… - International Journal of …, 2023 - mdpi.com
Biomaterials may enhance neural repair after spinal cord injury (SCI) and testing their
functionality in large animals is essential to achieve successful clinical translation. This work …

Spinal cord injury: Emerging technologies

AM Hersh, C Weber-Levine, K Jiang… - Neurosurgery …, 2024 - neurosurgery.theclinics.com
Described in antiquity as a “medical condition that should not be treated,” spinal cord injury
(SCI) has undergone a dramatic revolution in management that has improved both survival …

Porcine Models of Spinal Cord Injury

CA Wathen, YG Ghenbot, AK Ozturk, DK Cullen… - Biomedicines, 2023 - mdpi.com
Large animal models of spinal cord injury may be useful tools in facilitating the development
of translational therapies for spinal cord injury (SCI). Porcine models of SCI are of particular …

Spinal cord lesion MRI and behavioral outcomes in a miniature pig model of spinal cord injury: exploring preclinical potential through an ad hoc comparison with …

AC Smith, RU Ahmed, KA Weber… - Spinal Cord Series and …, 2024 - nature.com
Study design prospective case series of Yucatan miniature pig spinal cord contusion injury
model with comparison to human cases of spinal cord injury (SCI). Objectives to describe …

[HTML][HTML] A 72-h sedated porcine model of traumatic spinal cord injury

MM Thygesen, S Entezari, N Houlind, TH Nielsen… - Brain and Spine, 2024 - Elsevier
Introduction There is an increasing focus on the prevention of secondary injuries following
traumatic spinal cord injury (TSCI), especially through improvement of spinal cord perfusion …

[HTML][HTML] Isolation and characterization of mammary epithelial cells derived from Göttingen Minipigs: A comparative study versus hybrid pig cells from the IMI …

C Bernardini, S Nesci, D La Mantia, R Salaroli… - Research in Veterinary …, 2024 - Elsevier
The value of pig as “large animal model” is a well-known tool for translational medicine, but
it can also be beneficial in studying animal health in a one-health vision. The ConcePTION …

[HTML][HTML] Bridging the gap: a translational perspective in spinal cord injury

OI Hassan, S Takamiya… - Experimental …, 2024 - pmc.ncbi.nlm.nih.gov
Traumatic spinal cord injury (SCI) is a devastating and complex condition to treat with no
curative options. In the past few decades, rapid advancements in our understanding of SCI …

[PDF][PDF] Topical application of hypothermia in a porcine spinal cord injury model

I Šulla, S Horňák, Š Papcúnová - Folia Veterinaria, 2023 - sciendo.com
Spinal cord injuries (SCIs) are catastrophic events in humans and animals. They often result
in permanent loss of motor, sensory, and autonomic functions caudally from the site of the …