Background The efficacy and safety of platelet-rich plasma (PRP) augmentation for
arthroscopic meniscal repair is controversial. This meta-analysis compared arthroscopic …

Purpose It is unclear whether the results of arthroscopic partial meniscectomy (APM) are
comparable to a structured physical therapy (PT). This systematic review investigated …

Background: Clinical results after isolated meniscal repair are not always satisfactory, with
an overall failure rate of around 25%. To improve the success rate of meniscal repair …

Background: Post-traumatic joint contracture (PTJC) mainly manifests as excessive
inflammation leading to joint capsule fibrosis. Transforming growth factor (TGF)-β1, a key …

Background There is conflicting clinical evidence whether platelet-rich plasma (PRP)
therapies could translate to an increased meniscus healing rate and improved functional …

Following most injuries to a musculoskeletal tissue which function in unique mechanical
environments, an inflammatory response occurs to facilitate endogenous repair. This is a …

Orthoregeneration is defined as a solution for orthopedic conditions that harnesses the
benefits of biology to improve healing, reduce pain, improve function, and optimally, provide …

Orthobiologics are rapidly growing in use given their potential to augment healing for
multiple musculoskeletal conditions. Orthobiologics consist of a variety of treatments …

Purpose To evaluate the cost-effectiveness of 3 isolated meniscal repair (IMR) treatment
strategies: platelet-rich plasma (PRP)–augmented IMR, IMR with a marrow venting …

Background Menisci, one of the most important anatomical structures of the knee joint, plays
a role in load transfer, stability, shock absorption, prevention of articular cartilage …