Background The management of postoperative pain and recovery is still unsatisfactory in a
number of cases in clinical practice. Opioids used for postoperative analgesia are frequently …

Postoperative cognitive dysfunction (POCD) is a common complication of the surgical
experience and is common in the elderly and patients with preexisting neurocognitive …

Abstract Post-Operative Cognitive Dysfunction (POCD) is a highly prevalent condition with
significant clinical, social and financial impacts for patients and their communities. The …

Perioperative pain management is a unique challenge in patients undergoing spine surgery
due to the increased incidence of both pre-existing chronic pain conditions and chronic …

Lidocaine has analgesic effect and antihyperalgesic and anti-inflammatory properties, which
enable its use as a general anesthetic adjuvant. Lidocaine can reduce nociception and/or …

Perioperative pain management is a significant challenge following major spine surgery.
Many pathways contribute to perioperative pain, including nociceptive, inflammatory, and …

The use of opioids in the perioperative period is associated with respiratory depression,
impaired gastrointestinal function, post-operative nausea and vomiting (PONV), pruritus …

Background Postoperative cognitive dysfunction (POCD) has been reported as a significant
complication in elderly patients. Various methods have been proposed for reducing the …

Objectives: To investigate the effects of obesity caused by high-fat diet (HFD) on
postoperative cognitive dysfunction (POCD) and expression of the Sirt1/PGC …

Even after successful hip arthroplasty, elderly patients who have undergone this procedure
remain subject to cognitive decline and may collectively develop postoperative cognitive …