Natural killer cells (NK cells) are the first line of the innate immune defense system, primarily
located in peripheral circulation and lymphoid tissues. They kill virally infected and …

Human natural killer (NK) cells can be subdivided into different populations based on the
relative expression of the surface markers CD16 and CD56. The two major subsets are …

NK cells have therapeutic potential for a wide variety of human malignancies. However,
because NK cells expand poorly in vitro, have limited life spans in viv o, and represent a …

Natural Killer (NK) cells are cytotoxic lymphocytes of the innate immune system and play a
critical role in anti-viral and anti-tumor responses. NK cells develop in the bone marrow from …

Natural killer (NK) cells are a promising tool for the use in adoptive immunotherapy, since
they efficiently recognize and kill tumor cells. In this context, ex vivo cultivation is an …

Adoptive immunotherapy with natural killer cells was pioneered 30 years ago in human
clinical trials with the development of cytokine‐induced killer cells—unfractionated …

The administration of ex vivo expanded natural killer (NK) cells as potential antitumor
effector cells appears to be suitable for effector cell-based immunotherapies in high-risk …

Initially described as effectors of natural cytotoxicity and critical players for the control of viral
infections and tumor growth, recent investigations unraveled more widespread functions for …

Natural killer (NK) cell‐based immunotherapy holds prominent potential for cancer
treatment. However, its application in solid tumors is limited by a rapid decline in viability …

Natural Killer (NK) cells are innate lymphocytes able to mediate immune-surveillance and
clearance of viral infected and tumor-transformed cells. Growing experimental and clinical …