2024 heart disease and stroke statistics: a report of US and global data from the American Heart Association

SS Martin, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

Mendelian randomization for cardiovascular diseases: principles and applications

SC Larsson, AS Butterworth… - European heart journal, 2023 - academic.oup.com
Large-scale genome-wide association studies conducted over the last decade have
uncovered numerous genetic variants associated with cardiometabolic traits and risk factors …

Physiology of sedentary behavior

AJ Pinto, A Bergouignan, PC Dempsey… - Physiological …, 2023 - journals.physiology.org
Sedentary behaviors (SB) are characterized by low energy expenditure while in a sitting or
reclining posture. Evidence relevant to understanding the physiology of SB can be derived …

Multivariate genomic analysis of 5 million people elucidates the genetic architecture of shared components of the metabolic syndrome

S Park, S Kim, B Kim, DS Kim, J Kim, Y Ahn, H Kim… - Nature Genetics, 2024 - nature.com
Metabolic syndrome (MetS) is a complex hereditary condition comprising various metabolic
traits as risk factors. Although the genetics of individual MetS components have been …

[HTML][HTML] Dose–response associations, physical activity intensity and mortality risk: A narrative review

U Ekelund, MA Sanchez-Lastra, KE Dalene… - Journal of Sport and …, 2024 - Elsevier
Physical activity is consistently associated with reduced mortality, decreased risk for non-
communicable diseases, and improved mental health in observational studies. Randomized …

The Rotterdam Study. Design update and major findings between 2020 and 2024

MA Ikram, BCT Kieboom, WP Brouwer… - European Journal of …, 2024 - Springer
Abstract The Rotterdam Study is a population-based cohort study, started in 1990 in the
district of Ommoord in the city of Rotterdam, the Netherlands, with the aim to describe the …

Hepatitis B virus infection: An insight into the clinical connection and molecular interaction between hepatitis B virus and host extrahepatic cancer risk

Y Min, X Wei, X Xia, Z Wei, R Li, J Jin, Z Liu… - Frontiers in …, 2023 - frontiersin.org
The evidence for chronic hepatitis B virus (HBV) infection and hepatocellular carcinoma
(HCC) occurrence is well established. The hepatocyte epithelium carcinogenesis caused by …

CARE as a wearable derived feature linking circadian amplitude to human cognitive functions

S Cui, Q Lin, Y Gui, Y Zhang, H Lu, H Zhao… - NPJ Digital …, 2023 - nature.com
Circadian rhythms are crucial for regulating physiological and behavioral processes. Pineal
hormone melatonin is often used to measure circadian amplitude but its collection is costly …

Physical activity, sedentary behavior, and type 2 diabetes: mendelian randomization analysis

S Yuan, X Li, Q Liu, Z Wang, X Jiang… - Journal of the …, 2023 - academic.oup.com
Context The causality and pathways of the associations between physical activity and
inactivity and the risk of type 2 diabetes remain inconclusive. Objective We conducted an …

Integrative modeling of accelerometry-derived sleep, physical activity, and circadian rhythm domains with current or remitted major depression

SJ Kang, A Leroux, W Guo, D Dey, MPF Strippoli… - JAMA …, 2024 - jamanetwork.com
Importance Accelerometry has been increasingly used as an objective index of sleep,
physical activity, and circadian rhythms in people with mood disorders. However, most prior …