Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms

G León, M Herrera, Á Segura, M Villalta, M Vargas… - Toxicon, 2013 - Elsevier
Snake antivenoms are formulations of immunoglobulins, or immunoglobulin fragments,
purified from the plasma of animals immunized with snake venoms. Their therapeutic …

Immune response towards snake venoms

G León, L Sánchez, A Hernández… - … & Allergy-Drug …, 2011 - ingentaconnect.com
The immune response involves a complex repertoire of innate and adaptive responses to
foreign agents in the organism. The present review focuses on the immune response to …

Hib vaccines: past, present, and future perspectives

AE Zarei, HA Almehdar… - Journal of immunology …, 2016 - Wiley Online Library
Haemophilus influenzae type b (Hib) causes many severe diseases, including epiglottitis,
pneumonia, sepsis, and meningitis. In developed countries, the annual incidence of …

Influence of camel milk on the hepatitis C virus burden of infected patients

EM El-Fakharany, NA El-Baky… - Experimental and …, 2017 - spandidos-publications.com
Hepatitis C virus (HCV) infection represents a world health problem and no protective
vaccine or effective drug currently exists. For economic reasons, many patients use …

Anti-infectivity of camel polyclonal antibodies against hepatitis C virus in Huh7. 5 hepatoma

EM El-Fakharany, N Abedelbaky, BM Haroun… - Virology journal, 2012 - Springer
Purpose To extend the study of the camel milk proteins which have antiviral activity against
HCV, camel naïve polyclonal IgGs, α-lactalbumin were purified from camel milk and their …

[HTML][HTML] Simple and efficient protocol for immunoglobulin Y purification from chicken egg yolk

EM Redwan, AA Aljadawi, VN Uversky - Poultry Science, 2021 - Elsevier
Besides being a common food component broadly consumed worldwide, egg yolk
immunoglobulin Y (IgY) has essential therapeutic potentials. In fact, in a time of ever …

Animal-derived pharmaceutical proteins

ELRM Redwan - Journal of Immunoassay and Immunochemistry®, 2009 - Taylor & Francis
Livestock animals have made a significant contribution to human health and well-being
throughout humankind's history. A significant contribution of farm animals to human health …

Development of a cost-effective ovine polyclonal antibody-based product, EBOTAb, to treat Ebola virus infection

SD Dowall, J Callan, A Zeltina… - The Journal of …, 2016 - academic.oup.com
The highly glycosylated glycoprotein spike of Ebola virus (EBOV-GP1, 2) is the primary
target of the humoral host response. Recombinant EBOV-GP ectodomain (EBOV-GP1 …

Monoclonal antibodies for the prevention of rabies: theory and clinical practice

T Nagarajan, WE Marissen… - Antibody Technology …, 2014 - Taylor & Francis
Monoclonal antibodies (MAbs) have become a unique and attractive class of biologics,
possessing several desirable characteristics for use in human medicine. Anti-infective MAbs …

[HTML][HTML] Development of a cost-effective ovine antibody-based therapy against SARS-CoV-2 infection and contribution of antibodies specific to the spike subunit …

S Findlay-Wilson, L Easterbrook, S Smith, N Pope… - Antiviral Research, 2022 - Elsevier
Antibodies against SARS-CoV-2 are important to generate protective immunity, with
convalescent plasma one of the first therapies approved. An alternative source of polyclonal …