The crown and the scepter: roles of the protein corona in nanomedicine

R Cai, C Chen - Advanced Materials, 2019 - Wiley Online Library
Engineering nanomaterials are increasingly considered promising and powerful biomedical
tools or devices for imaging, drug delivery, and cancer therapies, but few nanomaterials …

Current understanding of biological identity at the nanoscale and future prospects

KA Dawson, Y Yan - Nature nanotechnology, 2021 - nature.com
Nanoscale objects are processed by living organisms using highly evolved and
sophisticated endogenous cellular networks, specifically designed to manage objects of this …

Mesoporous silica nanoparticles as drug delivery vehicles in cancer

A Watermann, J Brieger - Nanomaterials, 2017 - mdpi.com
Even though cancer treatment has improved over the recent decades, still more specific and
effective treatment concepts are mandatory. Surgical removal is not always possible …

Graphene-based nanomaterials: the promising active agents for antibiotics-independent antibacterial applications

MY Xia, Y Xie, CH Yu, GY Chen, YH Li, T Zhang… - Journal of Controlled …, 2019 - Elsevier
Graphene-based nanomaterials, such as graphene oxide (GO) and reduced graphene
oxide (rGO), have shown great potentials in drug delivery and photodynamic/photothermal …

Deep exploration of random forest model boosts the interpretability of machine learning studies of complicated immune responses and lung burden of nanoparticles

F Yu, C Wei, P Deng, T Peng, X Hu - Science advances, 2021 - science.org
The development of machine learning provides solutions for predicting the complicated
immune responses and pharmacokinetics of nanoparticles (NPs) in vivo. However, highly …

Personalized protein corona on nanoparticles and its clinical implications

C Corbo, R Molinaro, M Tabatabaei… - Biomaterials …, 2017 - pubs.rsc.org
It is now well understood that once in contact with biological fluids, nanoscale objects lose
their original identity and acquire a new biological character, referred to as a protein corona …

Formation of the protein corona: the interface between nanoparticles and the immune system

F Barbero, L Russo, M Vitali, J Piella, I Salvo… - Seminars in …, 2017 - Elsevier
The interaction of inorganic nanoparticles and many biological fluids often withstands the
formation of a Protein Corona enveloping the nanoparticle. This Protein Corona provides the …

Scratching the surface of the protein corona: challenging measurements and controversies

PL Latreille, M Le Goas, S Salimi, J Robert… - ACS …, 2022 - ACS Publications
This Review aims to provide a systematic analysis of the literature regarding ongoing
debates in protein corona research. Our goal is to portray the current understanding of two …

The effect of nanoparticle size on the ability to cross the blood–brain barrier: an in vivo study

O Betzer, M Shilo, R Opochinsky, E Barnoy… - …, 2017 - Taylor & Francis
Aim: Our goal was to develop an efficient nanoparticle-based system that can overcome the
restrictive mechanism of the blood–brain barrier (BBB) by targeting insulin receptors and …

Biomimetic cell-derived nanocarriers in cancer research

E Soprano, E Polo, B Pelaz, P Del Pino - Journal of Nanobiotechnology, 2022 - Springer
Nanoparticles have now long demonstrated capabilities that make them attractive to use in
biology and medicine. Some of them, such as lipid nanoparticles (SARS-CoV-2 vaccines) or …