Most research on nutritional effects on aging has focussed on the impact of manipulating
single dietary factors such as total calorie intake or each of the macronutrients individually …

Insulin‐like peptides (ILPs) belong to the insulin superfamily and act as hormones,
neuromediators, and growth factors during the post‐embryonic life‐cycle stages of insects …

Macronutrient balance is an important determinant of fitness in many animals, including
insects. Previous studies have shown that altering the concentrations of yeast and sugar in …

Drosophila melanogaster has been widely used in the biological sciences as a model
organism. Drosophila has a relatively short life span of 60–80 days, which makes it attractive …

Dietary restriction extends lifespan in a variety of organisms, but the key nutritional
components driving this process and how they interact remain uncertain. In Drosophila …

Age-related impairment of angiogenesis is likely to play a central role in
cerebromicrovascular rarefaction and development of vascular cognitive impairment, but the …

Sex differences in lifespan are well recognized in the majority of animal species. For
example, in male versus female Drosophila melanogaster there are significant differences in …

The effects of sucrose in varied concentrations (0.25–20%) with constant amount of yeasts in
larval diet on development and metabolic parameters of adult fruit fly Drosophila …

Fruit flies have eight identified Drosophila insulin-like peptides (DILPs) that are involved in
the regulation of carbohydrate concentrations in hemolymph as well as in accumulation of …

The target of rapamycin (TOR) pathway integrates signals from extracellular and intracellular
agents, such as growth factors, nutrients, mediators of energy balance, oxygen availability …