Triple-negative breast cancer (TNBC) is the most aggressive and hard-to-treat form of breast
cancer. TNBC has a higher propensity for earlier relapse and an increased risk of metastasis …

Metal complexes have shown promise as photosensitizers for cancer diagnosis and
therapeutics. However, the vast majority of metal photosensitizers are not ideal and …

Osteoarthritis (OA) is a low‐grade inflammatory and progressive joint disease, and its
progression is closely associated with an imbalance in M1/M2 synovial macrophages …

Phosphoglycerate dehydrogenase (PHGDH), the rate-limiting enzyme in the first step of the
serine synthesis pathway (SSP), is overexpressed in multiple types of cancers. The …

Metabolic adaptations can help cancer cells to escape from chemotherapeutics, mainly
involving autophagy and ATP production. Herein, we report a new rhein‐based …

Nanostructure-based functions are omnipresent in nature and essential for the diversity of
life. Unlike small molecules, which are often inhibitors of enzymes or biomimetics with …

Purinergic signalling, consisting of extracellular purines and purinergic receptors, modulates
cell proliferation, invasion and immunological reaction during cancer progression. Here, we …

Dendritic cells (DCs) are crucial mediators of innate and adaptive antitumor immunity,
whereas exogenously and endogenously driven lipid accumulation causes immune …

To targeted overcome the multidrug resistance (MDR) and metastasis of liver tumors, we
proposed to develop a palladium (Pd) agent based on a specific residue of human serum …

Cadmium (Cd) is a widely used heavy metal and has recently been recognized as a
possible source of human toxicity due to its ability to accumulate in organs. Accumulation of …