Pancreatic β-cell failure and death contribute significantly to the pathogenesis of type 2
diabetes. One of the main factors responsible for β-cell dysfunction and subsequent cell …

Background Human serum albumin is the principal protein in human serum. It participates in
regulation of plasma oncotic pressure and transports endogenous and exogenous ligands …

Albumin is the most abundant protein in blood plasma and acts as a carrier for many
circulating molecules. Hypoalbuminaemia, mostly caused by either renal or liver disease or …

Abstract G-protein-coupled receptor 40 (GPR40), known as free fatty acid receptor 1, is
mainly expressed in pancreatic β-cells and activated by medium-and long-chain fatty acids …

Autophagy is an evolutionarily conserved degradative process that allows cells to maintain
homoeostasis in numerous physiological situations. This process also functions as an …

The effect of structured triacylglycerols [1-oleoyl-2-palmitoyl-3-linoleoylglycerol (OPL), 3-
dilinoleoyl-2-palmitoylglycerol (LPL), and 1, 3-dioleoyl-2-palmitoylglycerol (OPO)] in human …

采用软脂酸诱导3T3-L1 脂肪细胞胰岛素抵抗后, 给予不同剂量的六堡茶水提物治疗,
探讨六堡茶对胰岛素抵抗3T3-L1 脂肪细胞的糖脂代谢的影响. 结果表明, 1 mmol· L-1 …

Human amniotic membrane (hAM) represents a tissue that is well established as biomaterial
in the clinics with potential for new applications in regenerative medicine. For tissue …

Abstract In the past 2–3 decades, numerous attempts have been made to create an insulin‐
secreting β cell line that maintains normal insulin secretion. However, primary β cell cultures …

Metabolic inflammatory damage, characterized by Toll‐like receptor 4 (TLR4) signaling
activation, is a major mechanism underlying lipotoxicity‐induced β‐cell damage. The …